Accelerate to Discover

Back to filter

Related topics

Abnormal capillary vasodynamics contribute to ictal neurodegeneration in epilepsy

Mauna Kea Technologies

Sep 22, 2017

In this scientific article from Leal-Campanario et al., the Cellvizio Dual band is used to track in real time capillary...

Digital measurement for HER2 amplifcation in HER2 equivocal breast cancer diagnosis

RainDance Technologies

Sep 20, 2017

Wang et al., in their paper have compared 2 diferent dPCR platforms and the accuracy of dPCR compared with the standard...

Linked-read sequencing combined with optical mapping produce a high quality mammalian genome

BioNano Genomics

Sep 18, 2017

Here, we have evaluated two technologies for assembling a de novo mammalian genome of the Hawaiian monk seal, an...

Red-shifted firefly luciferase optimized for Candida albicans in vivo bioluminescence imaging

Bruker Biospin

Sep 15, 2017

Candida albicans is a major fungal pathogen causing life-threatening diseases in immuno-compromised patients. As these...

Sep 25, 2017

Real-time, dynamic measurements of cellular migration & controlled microenvironmental conditions

Fluxion Biosciences

Sep 13, 2017

Cellular migration is an important biological process that occurs in both in health and disease as a part of wound...

Timelapse analysis of cell migration using CQ1 confocal quantitative image cytometer

Yokogawa

Sep 6, 2017

The scratch assay is one of the most commonly used methods to evaluate the cellular capability of infiltration and...

Whole genome optical mapping reveals multiple fusion events chained by novel sequences in cancer

BioNano Genomics

Sep 5, 2017

Bionano Genomics optical mapping helps you reveal hidden structur variations (SVs). In cancer, acquired SVs have been...

Sep 25, 2017

In vivo imaging of the Muc5b gel-forming mucin

Mauna Kea Technologies

Aug 8, 2017

Gel-forming mucins are macromolecules produced by goblet cells and responsible for the mucus gel formation. Changes in...

Show all topics (10)

Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy

Sep 12, 2017

Using standard cell lines, although attractive, can lead to unexpected results and probably to important differences when investigating a drug in primary cell lines isolated from patients. The opportunity to use cells of human origin may improve the predictive value of assays in drug testing and came hand in hand with the development of innovative real-time monitoring of cellular behaviour.

xCELLigence real time cell analyser offers a label-free non-invasive manner long-term recording of cellular signals. Considering all this aspects, the aim of our research was to evaluate the impedance of the primary melanocytes isolated from excised tumours that were confirmed as cutaneous melanoma. Primary cell cultures were used for establishing the efficacy pattern of a standard cytostatic, dacarbazine.
Our goal stands for obtaining a work flow for validating specific drug’s efficacy in individual tumour cells as a mean to personalize therapy in melanoma.

Read more

Scientific paper

Related technologies: Real-time, Label Free Cell Analysis

Get more info

Riccardo Pasculli

Application Specialist

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

Related products

A unique, portable, impedance-based system for cell-based assays, such as cell growth, proliferation, cytotoxicity, adhesion and morphological dynamics

show detail

The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

show detail

Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

show detail

Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement

show detail

Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey