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High-resolution and high-sensitivity PET imaging of cardiovascular disease

Bruker Biospin

Apr 20, 2018

In this paper, Bruker report the recent progress in preclinical PET hardware development enabling now to reach...

Rapid, accurate diagnosis of Clostridium difficile infections

BJS Biotechnologies

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Real-time PCR of toxin genes has been shown to be the most effective diagnostic method for accurate and early diagnosis...

Target large genomic regions with 10x genomics using SageHLS

Sage Science

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With customized Cas9 nucleases, scientists can now isolate specific large genomic DNA fragments with the SageHLS...

Expert-led didactic versus self-directed audiovisual training of confocal laser endomicroscopy

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This randomized controlled study involved trainee analysts who were taught how to recognize mucosal barrier defects on...

Apr 24, 2018

Evaluation of quantum dot toxicity on three-dimensional spheroid using Lumascope720

Etaluma

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In this work, three-dimensional (3D) spheroid cultures of human adipose-derived mesenchymal stem cells (hAD-MSCs), with...

Direct label and stain chemistry is finally here

BioNano Genomics

Apr 3, 2018

Bionano direct label and stain (DLS) technology is a new, nondestructive chemistry for sequence motif labeling of...

Amphiphilic nanocarrier leads to improved therapeutic response in pancreatic cancer

Mauna Kea Technologies

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A promising strategy to treat cancer is knocking-down the expression of specific cancer-promoting genes by RNA...

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Fluxion Biosciences announces launch of ERASE-Seq NGS liquid biopsy analysis service

Fluxion Biosciences

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Cloud-based ERASE-Seq delivers ultra-high sensitivity somatic mutation detection using background error correction and...

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De novo sequence assembly using nanochannel arrays from BioNano Genomics

Apr 4, 2016

Next-generation sequencing (NGS) technologies have enabled high-throughput and low-cost generation of sequence data;however, de novo genome assembly remains a great challenge, particularly for large genomes. NGS short reads are often insufficient to create large contigs that span repeat sequences and to facilitate unambiguous assembly. Plant genomes are notorious for containing high quantities of repetitive elements, which combined with huge genome sizes, makes accurate assembly of these large and complex genomes intractable thus far. Using two-color genome mapping of tiling bacterial artificial chromosomes (BAC) clones on nanochannel arrays delivered by BioNano Genomics, scientists completed high-confidence assembly of a 2.1-Mb, highly repetitive region in the large and complex genome of Aegilops tauschii.

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Related technologies: Genome Mapping

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BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

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Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

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