Accelerate to Discover

Back to filter

Related topics

How to build the largest genome ever, in 3 easy steps

BioNano Genomics

Feb 23, 2018

Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined...

High-throughput observation of molecular motor activity & dynamics

LUMICKS

Feb 21, 2018

With LUMICKS’ C-Trap, it is possible to observe myosin activity,the processive motion, the binding kinetics along...

X-RAD SmART

Precision X-Ray

Feb 20, 2018

The X-RAD SmART Image Guided Irradiator for small animals provides the most advanced and accurate treatment...

xxcloud – thermal cycler software

BJS Biotechnologies

Feb 16, 2018

Tired of waiting in line to use a qPCR system? The wait is over… the xxcloud is here! The xxcloud is exciting new...

Feb 25, 2018

BioNano mapping outperforms existing clinical tests in Duchenne´s muscular dystrophy patients

BioNano Genomics

Feb 15, 2018

In a publication in Genome Medicine, a team of researchers from Children’s National Health Center and University of...

Label-free, real-time live-cell assays for spheroids: IncuCyte bright-field analysis

Sartorius

Feb 12, 2018

A  growing  body  of  evidence  suggests  that  more  relevant  and  translational  observations  can  be  made  with ...

Measuring absolute blood perfusion in mice using dynamic contrast-enhanced ultrasound

VisualSonics FujiFilm

Feb 8, 2018

Contrast-enhanced ultrasound imaging involves the injection of gas-filled microbubbles that do not extravasate. This...

Feb 25, 2018

Nanoparticle-uptake behavior in two standard cell lines, NIH/3T3 and A549

Etaluma

Feb 7, 2018

The uptake of nanomaterials into different cell types is a key issue for the determination of nanotoxicity as well as...

Show all topics (10)

Human solid tumor cytomics: revealing novel melanoma and immune cell subsets

Jun 27, 2016

We know that cellular heterogeneity in the tumor microenvironment complicates the diagnosis and treatment of cancer. Tumors are complex, dynamic systems composed of diverse cell types in various functional states, including cancer cells and infiltrating immune cells. Resolving this cellular heterogeneity requires a single-cell approach, as analyses on bulk cell preparations mask the heterogeneity and complexity of the biological system and may lead researchers down the wrong path.
Cutting-edge single-cell analysis tools for exploring the genomic, transcriptomic and proteomic states of both tumor and related immune cells are enabling researchers to understand system heterogeneity, identify cells with previously unrecognized phenotypes and elucidate important therapeutic mechanisms.
Tumors are composed of diverse cell types, including cancer cells that can differentially evade therapy and immune cells that may aid or impede treatment. This webinar highlights high-content single-cell approaches developed by the Irish lab for systems immunology and cancer biology studies of human solid tumors, including melanoma and brain cancer. It also discusses technical and biological quality controls, computational analysis and the strengths of combining single-cell approaches, such as mass cytometry, phospho-flow, imaging, transcript profiling and sequencing. These cytomic approaches are especially powerful for dissecting cellular mechanisms of treatment response, monitoring key biomarkers and precise targeting of clinically relevant cell subsets.
Click to watch the video: https://www.fluidigm.com/media#075976ec-8d88-4516-b438-2909ad8f01b0

 

Application
Product news

Related technologies: Automated Single-cell Genomics

Brand profile

Fluidigm

Fluidigm is a Molecular and Single Cell Biology company that creates microfluidic-based chips and instrumentation for Life-Science research.

Related products

A new standard for high-throughput real-time PCR, end-point PCR and digital PCR

show detail

The first automated solution for single-cell genomics, now capable of even more

show detail

Time-of-Flight Mass Cytometer for highly multi-parametric single cell data

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey