Accelerate to Discover

Back to filter

Related topics

Abnormal capillary vasodynamics contribute to ictal neurodegeneration in epilepsy

Mauna Kea Technologies

Sep 22, 2017

In this scientific article from Leal-Campanario et al., the Cellvizio Dual band is used to track in real time capillary...

Digital measurement for HER2 amplifcation in HER2 equivocal breast cancer diagnosis

RainDance Technologies

Sep 20, 2017

Wang et al., in their paper have compared 2 diferent dPCR platforms and the accuracy of dPCR compared with the standard...

Linked-read sequencing combined with optical mapping produce a high quality mammalian genome

BioNano Genomics

Sep 18, 2017

Here, we have evaluated two technologies for assembling a de novo mammalian genome of the Hawaiian monk seal, an...

Red-shifted firefly luciferase optimized for Candida albicans in vivo bioluminescence imaging

Bruker Biospin

Sep 15, 2017

Candida albicans is a major fungal pathogen causing life-threatening diseases in immuno-compromised patients. As these...

Sep 25, 2017

Real-time, dynamic measurements of cellular migration & controlled microenvironmental conditions

Fluxion Biosciences

Sep 13, 2017

Cellular migration is an important biological process that occurs in both in health and disease as a part of wound...

Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy

Acea Biosciences

Sep 12, 2017

There are a few literature data focusing on impedance measurement of melanocytes’ cellular behaviour. We present herein...

Timelapse analysis of cell migration using CQ1 confocal quantitative image cytometer

Yokogawa

Sep 6, 2017

The scratch assay is one of the most commonly used methods to evaluate the cellular capability of infiltration and...

Sep 25, 2017

Whole genome optical mapping reveals multiple fusion events chained by novel sequences in cancer

BioNano Genomics

Sep 5, 2017

Bionano Genomics optical mapping helps you reveal hidden structur variations (SVs). In cancer, acquired SVs have been...

Show all topics (10)

Hypoxia activates constitutive Luciferase reporter constructs

Jul 13, 2017

Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.

Read more

 

Scientific paper

Get more info

Riccardo Pasculli

Application Specialist

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

COY Laboratory Products

Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.

Related products

The Flexible nature of the unit allows for the user to reach deeper and higher into the unit

show detail

Gloveless Anaerobic Chambers offer the operator a convenient glove-free ability to handle and inspect samples under low oxygen (0-5 ppm) conditions

show detail

InVitro glove boxes – incubation, culture maintenance and analysis in the same environment

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey