Accelerate to Discover

Back to filter

Related topics

xxcloud – thermal cycler software

BJS Biotechnologies

Feb 16, 2018

Tired of waiting in line to use a qPCR system? The wait is over… the xxcloud is here! The xxcloud is exciting new...

BioNano mapping outperforms existing clinical tests in Duchenne´s muscular dystrophy patients

BioNano Genomics

Feb 15, 2018

In a publication in Genome Medicine, a team of researchers from Children’s National Health Center and University of...

Label-free, real-time live-cell assays for spheroids: IncuCyte bright-field analysis

Sartorius

Feb 12, 2018

A  growing  body  of  evidence  suggests  that  more  relevant  and  translational  observations  can  be  made  with ...

Measuring absolute blood perfusion in mice using dynamic contrast-enhanced ultrasound

VisualSonics FujiFilm

Feb 8, 2018

Contrast-enhanced ultrasound imaging involves the injection of gas-filled microbubbles that do not extravasate. This...

Feb 20, 2018

Nanoparticle-uptake behavior in two standard cell lines, NIH/3T3 and A549

Etaluma

Feb 7, 2018

The uptake of nanomaterials into different cell types is a key issue for the determination of nanotoxicity as well as...

Mapping and phasing of structural variation in patient genomes using nanopore sequencing

Sage Science

Feb 6, 2018

Scientists used the Oxford MinION nanopore sequencer with a novel pipeline, NanoSV, to detect structural variants from...

De novo design of a biologically active amyloid

Mauna Kea Technologies

Feb 5, 2018

Short amyloidogenic protein fragment can induce the aggregation of a protein normally not associated with amyloidosis...

Feb 20, 2018

Exploration of melanoma metastases in mice brains using endogenous contrast photoacoustic imaging

VisualSonics FujiFilm

Feb 2, 2018

This recent article by Lavaud et al., uses high-frequency ultrasound and spectroscopic photoacoustic imaging as a...

Show all topics (10)

Label-free toxicology analysis

Aug 30, 2016

Cell counting, confluence and morphology are useful parameters for toxicity analysis. The HoloMonitor time-lapse cytometer determines cell proliferation, both by cell counting and by confluence, but also allows for quantitative assessments of cell morphology. Healthy cells are irregular and rather thin, dying cells are small, less irregular and thick, while dead cells are round and thin. These features are the basics for determination of drug effects on cell populations.

Using HoloMonitor, cell proliferation, cell morphology and cell viability can be measured at several time points. Individual cells and whole cell populations are analyzed at the same time. This makes it possible to conveniently evaluate several different toxicological parameters using very few cell samples. The data become more relevant when the same samples are studied, than when separate, replicate cultures
are used for different time points and parameters. This contributes to building statistically sound results.

Application
Product news

Brand profile

Phase Holographic Imaging

Holographic technology allows the long-term behavior of living cells to be observed and quantified without toxic stains.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey