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From thousands of SVS to a handful of candidate genes

BioNano Genomics

Mar 1, 2018

Bionano’s Variant Annotation Pipeline (VAP) saves researchers valuable time (and frustration) by annotating structural...

Protectome analysis: A new selective tool for bacterial vaccine discovery

Acea Biosciences

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New generation vaccines are in demand to include only the key antigens sufficient to confer protective immunity among...

Follow biological processes in vivo at the cellular level

Mauna Kea Technologies

Feb 27, 2018

Cellvizio Lab uses unique probe-based Confocal Laser Endomicroscopy technology. Watch this recorded webinar to learn...

A novel real time imaging platform to quantify Macrophage Phagocytosis


Feb 26, 2018

Phagocytosis is a specific form of endocytosis by which cells engulf and internalize solid matter. Macrophages,...

Mar 18, 2018

How to build the largest genome ever, in 3 easy steps

BioNano Genomics

Feb 23, 2018

Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined...

Timelapse imaging of Drosophila melanogaster larva's central nervous system


Feb 22, 2018

Drosophila melanogaster is a well-established model organism to understand biological processes and study human...

High-throughput observation of molecular motor activity & dynamics


Feb 21, 2018

With LUMICKS’ C-Trap, it is possible to observe myosin activity,the processive motion, the binding kinetics along...

Mar 18, 2018

A novel real-time CTL assay to measure designer T-cell function against HIV Env(+) cells

Acea Biosciences

Feb 19, 2018

To increase the immunosurveillance in HIV infection, we used retroviral vectors expressing CD4-chimeric antigen...

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Non-invasive fluorescence imaging of infiltration in a mouse model of acute lung inflammation

Nov 29, 2016

The presence of bacterial endotoxin, lipopolysaccharide (LPS) in the lung can induce a major inflammatory response leading to acute lung injury. LPS is thought to immediately activate resident macrophages, leading to the production of various cytokines, including TNF-α. This will, in turn, prompt the recruitment of inflammatory cells, mainly neutrophils, into the lung through increases in capillary permeability and alveolar edema.1 Neutrophil infiltration into the lung can be monitored by certain, activatable (smart) fluorescent probes. This study evaluates the use of an activatable optical probe that is
optically silent upon inhalation and produces a fluorescent signal only after selective cleavage by the serine protease elastase produced by neutrophils.

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