Accelerate to Discover

Back to filter

Related topics

Inhibition of T cell receptor signaling mediated Calcium flux in T cells

Apr 23, 2018

Calcium (Ca2+) is an important secondary messenger and a key component of many cell processes. It is an extremely...

High-resolution and high-sensitivity PET imaging of cardiovascular disease

Bruker Biospin

Apr 20, 2018

In this paper, Bruker report the recent progress in preclinical PET hardware development enabling now to reach...

Rapid, accurate diagnosis of Clostridium difficile infections

BJS Biotechnologies

Apr 19, 2018

Real-time PCR of toxin genes has been shown to be the most effective diagnostic method for accurate and early diagnosis...

3D culture systems for 3D world

Synthecon

Apr 18, 2018

Synthecon, Incorporated is a biotechnology company that specializes in the design and manufacture of 3D cell culture...

Apr 24, 2018

Target large genomic regions with 10x genomics using SageHLS

Sage Science

Apr 16, 2018

With customized Cas9 nucleases, scientists can now isolate specific large genomic DNA fragments with the SageHLS...

Expert-led didactic versus self-directed audiovisual training of confocal laser endomicroscopy

Mauna Kea Technologies

Apr 16, 2018

This randomized controlled study involved trainee analysts who were taught how to recognize mucosal barrier defects on...

The effects of hypoxia and hydrostatic pressure in translational research

Xcell Biosciences

Apr 16, 2018

In vitro growth of cells in conditions close to native conditions and comparison to regular in vitro cultivation helped...

Apr 24, 2018

Evaluation of quantum dot toxicity on three-dimensional spheroid using Lumascope720

Etaluma

Apr 12, 2018

In this work, three-dimensional (3D) spheroid cultures of human adipose-derived mesenchymal stem cells (hAD-MSCs), with...

Show all topics (10)

Optical tweezers measurements of DNA conformational dynamics at the single-molecule level

Dec 4, 2017

DNA breathing, also known as fraying, describes the spontaneous local conformational transitions occurring within double-stranded DNA (dsDNA). Due to the transient and spontaneous nature of this process, the study of real-time DNA breathing transitions at the single-molecule level requires the use of highly sensitive experimentation technologies. Using LUMICKS’ high resolution optical tweezers, small and transient DNA conformational changes can be monitored in real-time, with an unprecedented stability, which provides scientists with valuable information on the number and frequency of various conformational stages.

Read more

Scientific paper
Technical breakthrough
Application

Related technologies: Single-molecule Interactions

Get more info

Regina Fillerová

Field Application Specialist

Regina

Fillerová

+420 731 127 718

Send Message

Brand profile

LUMICKS

Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics. 

Related products

Live, simultaneous and correlative visualization and manipulation of molecular interactions with sub-picoNewton force resolution and sub-nm position resolution.

show detail

Acoustic Force Spectroscopy is a single-molecule, lab-on-a-chip technology in which acoustic waves are used to exert forces on thousands of biomolecules.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey