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Abnormal capillary vasodynamics contribute to ictal neurodegeneration in epilepsy

Mauna Kea Technologies

Sep 22, 2017

In this scientific article from Leal-Campanario et al., the Cellvizio Dual band is used to track in real time capillary...

Digital measurement for HER2 amplifcation in HER2 equivocal breast cancer diagnosis

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Wang et al., in their paper have compared 2 diferent dPCR platforms and the accuracy of dPCR compared with the standard...

Linked-read sequencing combined with optical mapping produce a high quality mammalian genome

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Here, we have evaluated two technologies for assembling a de novo mammalian genome of the Hawaiian monk seal, an...

Red-shifted firefly luciferase optimized for Candida albicans in vivo bioluminescence imaging

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Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy

Acea Biosciences

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There are a few literature data focusing on impedance measurement of melanocytes’ cellular behaviour. We present herein...

The new xxsealer SA for the fasteast qPCR thermal cycler in the world

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Timelapse analysis of cell migration using CQ1 confocal quantitative image cytometer

Yokogawa

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The scratch assay is one of the most commonly used methods to evaluate the cellular capability of infiltration and...

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Whole genome optical mapping reveals multiple fusion events chained by novel sequences in cancer

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Bionano Genomics optical mapping helps you reveal hidden structur variations (SVs). In cancer, acquired SVs have been...

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Real-time, dynamic measurements of cellular migration & controlled microenvironmental conditions

Sep 13, 2017

Typically, cellular migration is studied using a two compartment device called a Boyden chamber or a transwell insert system. The data gathered using a Boyden chamber are narrowly-focused snapshots into complex biological phenomena. Events occurring before the endpoint are typically lost using the Boyden chamber or transwell approach. The processing of transwell inserts for data capture is considerably labor-intensive. Further, it is impossible to control environmental conditions within the well due to the static nature of the assay. In order to examine these processes in detail over time, it is necessary to observe cells in situ.

BioFlux allows observation of chemotaxis and migration as a dynamic event:

- Up to 16 conditions tested in parallel

- Flexible format (liquid or gel) enables a wider range of assays

- Better quality data with real-time measurements in situ

- Minimizes variability with a continuous chemotactic gradient

- Saves time by collecting data direct from the assay with no transfer steps

- Assays can be performed label-free

 

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Riccardo Pasculli

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Riccardo

Pasculli

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Fluxion Biosciences

With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.

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