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From thousands of SVS to a handful of candidate genes

BioNano Genomics

Mar 1, 2018

Bionano’s Variant Annotation Pipeline (VAP) saves researchers valuable time (and frustration) by annotating structural...

Protectome analysis: A new selective tool for bacterial vaccine discovery

Acea Biosciences

Feb 28, 2018

New generation vaccines are in demand to include only the key antigens sufficient to confer protective immunity among...

A novel real time imaging platform to quantify Macrophage Phagocytosis


Feb 26, 2018

Phagocytosis is a specific form of endocytosis by which cells engulf and internalize solid matter. Macrophages,...

How to build the largest genome ever, in 3 easy steps

BioNano Genomics

Feb 23, 2018

Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined...

Mar 19, 2018

Timelapse imaging of Drosophila melanogaster larva's central nervous system


Feb 22, 2018

Drosophila melanogaster is a well-established model organism to understand biological processes and study human...

High-throughput observation of molecular motor activity & dynamics


Feb 21, 2018

With LUMICKS’ C-Trap, it is possible to observe myosin activity,the processive motion, the binding kinetics along...

A novel real-time CTL assay to measure designer T-cell function against HIV Env(+) cells

Acea Biosciences

Feb 19, 2018

To increase the immunosurveillance in HIV infection, we used retroviral vectors expressing CD4-chimeric antigen...

Mar 19, 2018

BioNano mapping outperforms existing clinical tests in Duchenne´s muscular dystrophy patients

BioNano Genomics

Feb 15, 2018

In a publication in Genome Medicine, a team of researchers from Children’s National Health Center and University of...

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Single-cell twitching chemotaxis in developing biofilms

Jan 24, 2017

Here we use microfluidic chemical gradients and massively parallel automated tracking to study the behavior of the pathogen Pseudomonas aeruginosa during early biofilm development. We show that individual cells can efficiently move toward chemo-attractants using pili-based “twitching” motility and the Chp chemosensory system. Moreover, we discovered the behavioral mechanism underlying this surface chemotaxis: cells reverse direction more frequently when moving away from chemoattractant sources. These corrective maneuvers are triggered rapidly, typically before a wayward cell has ventured a fraction of a micron. Our work shows that single bacteria can direct their motion with submicron precision and reveals the hidden potential for chemotaxis within bacterial biofilms.

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Related technologies: Cell Interaction Studies

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Fluxion Biosciences

With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.

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Core control system, integrated to any inverted microscope to introduce flow to your research

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System that offers a fully-integrated solution for automated, high throughput shear flow assays

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