Accelerate to Discover

Measuring absolute blood perfusion in mice using dynamic contrast-enhanced ultrasound

Contrast-enhanced ultrasound imaging involves the injection of gas-filled microbubbles that do not extravasate. This property makes them ideal contrast agents for longitudinal studies of drug therapies.

Feb 8, 2018

Scientific paper

De novo design of a biologically active amyloid

Short amyloidogenic protein fragment can induce the aggregation of a protein normally not associated with amyloidosis in a manner that recapitulates key biophysical and biochemical characteristics of natural amyloids. Read this article to learn more!

Feb 5, 2018

Scientific paper

Accelerate your biomedical research

"Albira PET/SPECT/CT allowed us in vivo imaging of dynamic biological processes, monitoring of cancers and infectious diseases in small animal models, including assessment of therapeutic response, and biodistribution of candidate drugs."

Assoc. Prof. M.D. Marian Hajdúch

Institute of Molecular and Translational Medicine, Palacky University, Olomouc, Czech Republic

Studying cancer biology and therapeutic targets using PET technology

In vivo imaging is at the heart of preclinical research into cancer biology and treatment. In this webinar, you will hear about one lab’s experience of integrating Bruker’s preclinical PET system into a hospital-based small-animal imaging lab.

Jan 18, 2018

Scientific paper

Exploration of melanoma metastases in mice brains using endogenous contrast photoacoustic imaging

This recent article by Lavaud et al., uses high-frequency ultrasound and spectroscopic photoacoustic imaging as a multimodal non-invasive examination tool for the assessment of melanoma brain tumors in an orthotropic mouse model. 

Feb 2, 2018

Scientific paper

ADSC-sheet transplantation to prevent stricture after esophageal endoscopic submucosal dissection

This study reports a successful method of endoscopical adipose tissue-derived stromal cell (ADSC)-sheet transplantation for esophageal stricture prevention after an extended endoscopic submucosal dissection (ESD) in a swine model.

Jan 25, 2018

Scientific paper

Accelerate your biomedical research

"The Cellvizio Dual Band is capable of achieving cell to sub-cell resolution in vivo, from surface to deep tissues. The system allow us to monitor multiple dynamic processes, physiological pathways or cellular interactions in vivo in the same animal over longitudinal studies."

Assoc.Prof. M.D. Jakub Otáhal

Czech Academy of Sciences, Institute of Physiology, Prague, Czech Republic

Fluorescent dyes enhance polymer visibility in biomedical imaging

Shape memory polymers are versatile materials that can change shape in response to thermal or other external stimuli. This versatility has drawn a lot of interest to SMPs as potential biomaterials for use in minimally invasive medical procedures.

Jan 29, 2018

Scientific paper

In-ovo magnetic resonance imaging

In this webinar, medical physicist Prof. Volker Rasche and Bruker’s MRI specialist Dr. Thomas Basse, will discuss how in-ovo MRI can be used to non-invasively monitor contrast agent-labelled compounds in CAM models of transplanted tumor cells.

Jan 23, 2018

Scientific paper

High-frequency ultrasound imaging of mouse cervical lymph nodes

The video describes the protocol of application of high-frequency ultrasound (HFUS) for imaging mouse cervical lymph nodes. This technique optimizes visualization and quantification of cervical lymph node morphology, volume and blood flow.

Dec 7, 2017

Scientific paper

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