Our perfusion bioreactor systems allow for continuous feeding of the cell culture chamber from an external media bottle. While the culture media continuously perfuses through the system, the 3D aggregates of cells and scaffolds are retained in the cell culture chamber by a porous perfusion core.
The media also flows through an external silicone oxygenator via a peristaltic pump to maintain the oxygen level. Media can be exchanged, sampled, or modified with or without stopping the vessel rotation during 3D cell culture.
Both single and dual vessel systems can be used with or without scaffolds to create 3D cell models.