Molecular technologies

Target Enrichment for NGS
Regina Fillerová

Field Application Specialist

Regina

Fillerová

+420 731 127 718

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Target Enrichment for NGS

Amp Up Your Targets

Next-Generation Sequencing (NGS) technologies have transformed life science research, enabling many new sequencing-based applications. One of the most promising is targeted sequencing, to identify variations relevant to cancer, disease research, and population genetics. Using NGS as the foundation for a targeted sequencing approach promises to provide quantitative insight into mutations, in context, in a single run, at greater throughput, and at lower cost than previously seen.

The Access Array System or SmartChip Nano-Well Technology, combined with next-generation sequencing, is a powerful approach for comprehensive genotyping, validation, and screening analyses, including SNP identification, sequence variation and mutation detection, DNA methylation mapping, and exon sequencing—across hundreds of samples.

Library preparation is the foundation for a successful targeted sequencing run. However, traditional methods create bottlenecks and introduce risk to quality and reproducibility through the high number of steps and touch points in the protocols. The Access Array System, through its system of controllers and integrated fluidic circuits (IFCs), and SmartChip Nano-Well Technology encapsulate library preparation to provide unparalleled quality amplicons. These systems take DNA from sample to sequence-ready.

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Target Enrichment for NGS products

Superior library preparation on the widest scale with a streamlined workflow and low costs

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Automated Shearers offering a simple and easy-to-use, reproducible, and controllable method of fragmenting DNA

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A fast, accurate and low-cost NGS target enrichment system that features award-winning instrumentation and pre-validated gene panels, as well as flexible open source options.

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