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"In our lab, we use microCT Skyscan 1276 for visualization of vasculature and cancer in mice model. Xtreme II is powerful tool for molecular imaging. In our research group, Xtreme II is commonly used to assess the biodistribution of novel drug candidates in small animal model."

Adam Novobilský, Ph.D.

Dept. Pharmacology and Immunotherapy, Veterinary Research Institute, Brno, Czech Republic

SkyScan 1176 - Bruker Biospin

With the world's highest spatial resolution

The SKYSCAN 1176 is a high performance in vivo micro-CT scanner for preclinical research. The large format 11 megapixel x-ray camera gives an unrivalled combination of resolution, image field size and scan speed - everything that is required in a busy and demanding biomedical research laboratory. Image field width up to 68 mm allows full body mouse and rat scanning and distal limb scanning for big animals, such as rabbits, at pixel sizes of 9, 18 and 35µm. Variable x-ray applied voltage and filters provide scanning flexibility to allow imaging of a wide range of samples from lung tissue to bone with titanium implants. Animal beds for rats and mice are available made of carbon fiber or polystyrene foam. An integrated physiological monitoring subsystem provides breathing and heart-beat gating for proven thoracic image improvement by synchronized acquisition.

The full range of SKYSCAN software is supplied, including fast volumetric reconstruction, software for 2D / 3D quantitative analysis and for realistic 3D visualization. The software for 4D time-resolved microtomography is also supplied as standard. The scanner can work in "push button" mode with scanning start/stop and protocol setting from the integrated touch screen. The touch screen has a force sensitive surface allowing normal response to a hand in gloves. The main control rack-mounted workstation is integrated below the scanner. The scanner can be optionally supplied with an integrated cluster of four powerful Dual-QuadCore workstations placed in the lower part of the scanner's body.

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http://www.bruker.com/products/preclinical-imaging/x-ray-micro-ct/skyscan-1176

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Bone imaging and analysis with microCT - Wednesday, August 3, 2016, 10 am and 5 pm CEST Analysing high resolution lung microCT datasets Spatial resolution testing of microCT MicroCT boosts bone graft research Lung and heart cyclical imaging, simplified Webinar recording: 4D monitoring of bone and (re)modeling events using in vivo micro-CT Micro-CT study of the anatomy of a grasshopper Micro-CT in 3D data integration and (Clinical) workflows for digital orthodontics Comparing image quality in Phase Contrast X-Ray Tomography Webinar recording: Ex vivo microangioCT, advances in microvascular imaging Monitoring Lung tumor using Bioluminescence, Fluorescence and microCT Implementation of Micro CT in CAD/CAM dentistry for image processing and soft computing Bruker´s micro-CT used for some of the World’s First in vivo COVID-19 Imaging Experiments The Role of Micro-CT in Imaging Breast Cancer Specimens MicroCT Applications in Lung research and Immunology Bruker MicroCT systems supporting quality control for refurbished FFP masks Micro-CT: Fancy gadget or indispensable technology towards quantification of lung diseases? Bruker webinar: Ear evolution in fossil mammals A Glimpse on physiological monitoring for the in vivo SKYSCAN Systems Bruker webinar : High-resolution exploration of ESM-based vascularized tissue-flaps Bruker webinar: Experiences in The Use of Micro-CT in Insect Research Micro-CT user meeting 2021 Ex Vivo dental imaging is directly translatable to the clinic
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