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Jul 18, 2018

The quantitative polymerase chain reaction is the methodology to determine the essential and dominant role of cNEUROG2...

B fibers are the best predictors of cardiac activity during Vagus nerve stimulation

Jul 17, 2018

Vagus nerve stimulation (VNS) is a promising therapy for many neurologic and psychiatric conditions. However,...

New technologies to uncover the molecular basis of disorders of sex development

Jul 13, 2018

Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel...

δT cells and CD8+ T cells targeting of breast cancer cells

Jul 11, 2018

Cancer stem cells (CSCs) are a large cause of metastasis in breast cancer. They are also very resistent to any...

Jul 18, 2018

Incucyte system used for generating single-cell-derived cancer-associated fibroblast clones

Jul 9, 2018

Single-cell-derived cancer-associated fibroblast (CAFs) were produced using Incucyte. These cells were used to help...

Real-time study of platelet formation under sheer-flow with Lumascope

Jun 18, 2018

Platelet formation was observed with Lumascope microscope in a uniform-sheer-flow biorector. Videos of the formation...

Early fetal sex determination using micro-volume of maternal plasma

Jun 16, 2018

A qPCR-based assay, SneakPeek Early Gender Test (Gateway Genomics) has been developed to determine fetal sex as early...

Jul 18, 2018

3R Compliant drug development studies

Jun 8, 2018

In preclinical imaging, magnetic resonance imaging (MRI) can be an attractive alternative to researchers who have...

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A novel high throughput assay for diagnosis by real-time monitoring of parasite motility

Jun 7, 2017

Here we describe a novel application for a real-time cell monitoring device (xCELLigence) that can simply and objectively assess anthelmintic effects by measuring parasite motility in real time in a fully automated high-throughput fashion. We quantitatively assessed motility and determined real time IC50 values of different anthelmintic drugs against several developmental stages of major helminth pathogens of humans and livestock, including larval Haemonchus contortus and Strongyloides ratti, and adult hookworms and blood flukes. The assay enabled quantification of the onset of egg hatching in real time, and the impact of drugs on hatch rate, as well as discriminating between the effects of drugs on motility of drug-susceptible and –resistant isolates of H. contortus.

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Scientific paper

Related technologies: Real-time, Label Free Cell Analysis

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