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Bruker announces acquisition of preclinical and molecular imaging research software provider PMOD
Aug 19, 2019
The PMOD software is widely used for the analysis of positron emission tomography (PET) studies in neurology,...
Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome
Aug 16, 2019
The BluePippin was used for High Pass DNA size selection prior to library construction. ONT Promethion was used for...
Next-generation cytogenetics is here
Aug 9, 2019
On ESHG 2019 conference several oral and poster presentations compared Bionano optical mapping to clinical cytogenetics...
Electroporation using Lumascope: A sustainable method for Adipogenous Mesenchymal Stem Cells
Aug 7, 2019
Human mesenchymal stem cells derived from adipose tissue (AD-hMSCs) represent a promising source for tissue engineering...
The best way to fragment DNA for genomic and paired end library construction
Aug 5, 2019
Digilab NextGen Shear DNA Shearing offers the simplest, most reproducible, and most controllable method available for...
Software Update: Bionano releases a new pipeline for low Aalelic fraction SVs
Jul 31, 2019
Bionano Solve v3.4 is a major update that introduces an entirely new pipeline to detect SVs at low allelic fraction and...
On-cartridge preparation and evaluation of 68Ga-, 89Zr- and 64Cu-precursors for cell radiolabelling
Jul 29, 2019
Method of on-cartridge formation of gallium-68, zirconium-89 and copper-64 complexes in small volumes suitable for cell...
CQ1 confocal quantitative image cytometer: fighting colon cancer with killer cells
Jul 2, 2019
Genetically modified immune cells can successfully destroy colon cancer cells. This has been demonstrated for the first...
Feb 19, 2018
Stimulated rhesus PBMCs with antibodies to CD3/CD28 and cotransduced T cells with CD4-CAR and maC46 vectors. CD4-CAR-transduced T cells were added to Env(+) 293T cells at E:T of 1:1. Killing of target cells was measured as reduced impedance. Has been observed gene expression in 60-70% of rhesus CD3(+) CD8(+) T cells with the individual vectors and in 35% of the cells with both vectors. CD4-CAR-transduced populations specifically killed Env(+) cells. In these studies, scientist showed that designer T cells were redirected to kill Env(+) cells. Control of viremia without HAART would revolutionize treatment for HIV patients.
Related technologies: Conventional flow cytometry
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