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Flash news - did you know, that you can use Singulator S100 also for plant research?

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Multiplex Live cell imaging and real-time biosensor measurement with xCELLigence eSight

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AMI HTX installation in CEMEX Iasi, Romania

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Presentation movie

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The new WOLF G2 instrument has significantly expanded the capabilities of gentle benchtop microfluidic cell sorting...

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A novel real-time CTL assay to measure designer T-cell function against HIV Env(+) cells

Feb 19, 2018

Stimulated rhesus PBMCs with antibodies to CD3/CD28 and cotransduced T cells with CD4-CAR and maC46 vectors. CD4-CAR-transduced T cells were added to Env(+) 293T cells at E:T of 1:1. Killing of target cells was measured as reduced impedance. Has been observed gene expression in 60-70% of rhesus CD3(+) CD8(+) T cells with the individual vectors and in 35% of the cells with both vectors. CD4-CAR-transduced populations specifically killed Env(+) cells. In these studies, scientist showed that designer T cells were redirected to kill Env(+) cells. Control of viremia without HAART would revolutionize treatment for HIV patients.

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Scientific paper

Related technologies: Conventional flow cytometry

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