Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.
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Albira Si enables enhanced imaging in cancer research
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A study by Pieve et al. published in Bioconjugate Chemistry examined the development of high target affinity PET probes for imaging HER3 in a female mice model and also evaluated two strategies for radiolabeling the HER3 affibody molecule for targeting.
One of the strategies involved using the Albira Si, a combined PET SPECT molecular imaging system. Utilization of a combined imaging system with CT can not only provide anatomical landmarking, it can also help researchers evaluate modifications related to disease progression.
Using the Albira Si, researchers were able to determine that [18F]AlF-NOTA-ZHER3:8698 may be an effective HER3 imaging agent. Only with instrumentation that allowed a molecular view to the extent provided by Albira Si were the researchers able to perform the in vivo experiment safely and efficiently.
Related technologies: PET, SPECT, CT
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