Accelerate to discover

Back to filter

Related topics

Introducing the first EV isolation column capable of running 100 mL samples.

IZON

May 21, 2019

As the EV field continues to grow and advance, so has the need for scalability in EV isolation. Izon is addressing this...

PET/CT Si78: Versatility in microCT dose, speed, & resolution

Bruker Biospin

May 9, 2019

The Bruker PET/CT Si78 now pairs total-body PET and SkyScan microCT technology. This combination offers the advanced...

Cell by cell lung cancer marker profiling using high-parameter spectral flow cytometry

Cytek Biosciences

May 2, 2019

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80-85% cases of lung cancer....

We are pleased to announce the launch of the xxpress NGx

BJS Biotechnologies

Apr 30, 2019

The new xxpress thermal cycler has an upgraded optics system that provides better channel separation and enhanced...

May 23, 2019

In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

Spectral Instruments Imaging

Apr 26, 2019

As a trace element nutrient, cobalt is critical for both prokaryotes and eukaryotes. In the current study, a turn-on...

Bionano Genomics news presented at AGBT 2019

BioNano Genomics

Apr 23, 2019

2019 is starting off with a bang for Bionano with higher throughput on Saphyr, easier and faster sample prep, detection...

Synthesis and characterization of functional nanofilm-coated live Immune cells using CQ1

Yokogawa

Apr 10, 2019

Layer-by-layer assembly techniques have been extensively studied in cell biology because of their simplicity of...

May 23, 2019

Product update: The high pass plus cassette

Sage Science

Apr 9, 2019

The high pass plus gel cassette is the newest addition to the Pippin family. It is dedicated to the BluePippin...

Show all topics (10)

Analysing high resolution lung microCT datasets

Jan 23, 2017

Historically researchers apply time consuming step serial sectioning and subsequent staining and imaging using light microscopy to analyse the lung morphometry. The data obtained using histology is limited to 2D and, as the pathology is often patchy, the results can be biased and incomplete due to heterogeneous pathological phenotypes. Obtaining an overall status of the entire lung is crucial for reliable and complete data. For instance, when screening the lung for metastasis: these can easily be missed when only a few cross sections are made.
In the method note “MN096_Analysing high resolution lung microCT datasets” a detailed step by step protocol describes how to perform structural analysis of the lung.
SkyScan software CTAn allows the automatic 3D structure thickness and structure separation analysis from high resolution scans. Structure thickness provides an insight in the distribution of the wall thickness of the airways and / or vasculature of the lungs. In addition, structure separation results in an output of the distribution of the airway diameters, similar as the mean chord length used in histo-pathological analysis. Both types of analysis also allow the possibility to visualize the results in 3D using the SkyScan CTVox volume rendering software.

Read more

Scientific paper
Product news

Related technologies: X-ray and micro computed tomography

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

In-vivo micro-CT with the world's highest spatial resolution

show detail

The world’s fastest, low-dose, high-resolution micro-CT

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey