Accelerate to discover

Back to filter

Related topics

Assessment of pro-arrhythmic effects using xCELLigence Cardio system and Pluricyte Cardiomyocytes

Acea Biosciences

Aug 21, 2019

The combination of Pluricyte Cardiomyocytes and the xCELLigence RTCA Cardio ECR system enables  detailed ...

Bruker announces acquisition of preclinical and molecular imaging research software provider PMOD

Bruker Biospin

Aug 19, 2019

The PMOD software is widely used for the analysis of positron emission tomography (PET) studies in neurology,...

Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome

Sage Science

Aug 16, 2019

The BluePippin was used for High Pass DNA size selection prior to library construction. ONT Promethion was used for...

Fluxion Biosciences launches custom liquid biopsy NGS panel development

Fluxion Biosciences

Aug 14, 2019

Fluxion a leading developer of precision solutions for life science research and diagnostics, announced that can...

Aug 21, 2019

Superior flow cytometry data with NEW Curiox Laminar Wash systems - centrifuge - less washing

Curiox

Aug 12, 2019

The Laminar Wash technology provides an advantage to scientists in processing suspension cells for flow cytometry....

Next-generation cytogenetics is here

BioNano Genomics

Aug 9, 2019

On ESHG 2019 conference several oral and poster presentations compared Bionano optical mapping to clinical cytogenetics...

Electroporation using Lumascope: A sustainable method for Adipogenous Mesenchymal Stem Cells

Etaluma

Aug 7, 2019

Human mesenchymal stem cells derived from adipose tissue (AD-hMSCs) represent a promising source for tissue engineering...

Aug 21, 2019

The best way to fragment DNA for genomic and paired end library construction

Digilab

Aug 5, 2019

Digilab NextGen Shear DNA Shearing offers the simplest, most reproducible, and most controllable method available for...

Show all topics (10)

Analysing high resolution lung microCT datasets

Jan 23, 2017

Historically researchers apply time consuming step serial sectioning and subsequent staining and imaging using light microscopy to analyse the lung morphometry. The data obtained using histology is limited to 2D and, as the pathology is often patchy, the results can be biased and incomplete due to heterogeneous pathological phenotypes. Obtaining an overall status of the entire lung is crucial for reliable and complete data. For instance, when screening the lung for metastasis: these can easily be missed when only a few cross sections are made.
In the method note “MN096_Analysing high resolution lung microCT datasets” a detailed step by step protocol describes how to perform structural analysis of the lung.
SkyScan software CTAn allows the automatic 3D structure thickness and structure separation analysis from high resolution scans. Structure thickness provides an insight in the distribution of the wall thickness of the airways and / or vasculature of the lungs. In addition, structure separation results in an output of the distribution of the airway diameters, similar as the mean chord length used in histo-pathological analysis. Both types of analysis also allow the possibility to visualize the results in 3D using the SkyScan CTVox volume rendering software.

Read more

Scientific paper
Product news

Related technologies: X-ray and micro computed tomography

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

In-vivo micro-CT with the world's highest spatial resolution

show detail

The world’s fastest, low-dose, high-resolution micro-CT

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey