Accelerate to Discover

Back to filter

Related topics

Method to quantify local force distribution within biomolecular systems

LUMICKS

May 24, 2018

The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA...

Bionano fall user workshop

BioNano Genomics

May 23, 2018

We are happy to announce the Bionano Genomics’ 2018 user workshop taking place in San Diego on October 15-16,...

Registering FDG/PET mouse and AMYViD/PET-CT rat studies to brain VOI atlases

Bruker Biospin

May 22, 2018

Preclinical NeuroPET is employed widely in studies of stroke, ischemia, addiction and eurodegenerative diseases. In...

Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated down-regulation

Etaluma

May 21, 2018

Adverse tissue responses to metal wear and corrosion products from CoCr alloy implants remain a great challenge to...

May 28, 2018

New protocol: Analyze small extracellular RNAs with PippinHT

Sage Science

May 18, 2018

We’re pleased to see that PippinHT is featured heavily in the protocol for DNA sizing steps following PCR...

Genoox, Bionano collaborate to enhance the detection of pathogenic SVs

BioNano Genomics

May 14, 2018

Bionano is now working with the global health company Genoox to develop a genome informatics workflow to integrate and...

Outstanding return on investment with the xxpress qPCR thermal cycler

BJS Biotechnologies

May 10, 2018

Find out just how much money you could save by switching to the xxpress qPCR thermal cycler,visit the cost savings...

May 28, 2018

AVATAR Improves transfection efficiency with high viability

Xcell Biosciences

May 9, 2018

AVATAR lets you create any cell type even novel ones, with efficient transfection that improves reprogramming rates...

Show all topics (10)

Analysing high resolution lung microCT datasets

Jan 23, 2017

Historically researchers apply time consuming step serial sectioning and subsequent staining and imaging using light microscopy to analyse the lung morphometry. The data obtained using histology is limited to 2D and, as the pathology is often patchy, the results can be biased and incomplete due to heterogeneous pathological phenotypes. Obtaining an overall status of the entire lung is crucial for reliable and complete data. For instance, when screening the lung for metastasis: these can easily be missed when only a few cross sections are made.
In the method note “MN096_Analysing high resolution lung microCT datasets” a detailed step by step protocol describes how to perform structural analysis of the lung.
SkyScan software CTAn allows the automatic 3D structure thickness and structure separation analysis from high resolution scans. Structure thickness provides an insight in the distribution of the wall thickness of the airways and / or vasculature of the lungs. In addition, structure separation results in an output of the distribution of the airway diameters, similar as the mean chord length used in histo-pathological analysis. Both types of analysis also allow the possibility to visualize the results in 3D using the SkyScan CTVox volume rendering software.

Read more

Scientific paper
Product news

Related technologies: X-ray and Micro Computed Tomography

Get more info

Miroslav Vecheta

Support Specialist

Miroslav

Vecheta

+420 737 202 127

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

In-vivo micro-CT with the world's highest spatial resolution.

show detail

The world’s fastest, low-dose, high-resolution micro-CT

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey