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Facioscapulohumeral muscular dystrophy is characterized by a contraction of D4Z4 repeat array on chromosome 4 (chr4). Bionano FSHD EnFocus analysis enables accurate measurement of D4Z4 array on chr4 in as little as 3 days, starting with blood samples. The workflow starts with ultra-high molecular weight DNA isolation using Bionano prep SP blood and cell culture DNA isolation kit. This DNA is labeled with a Direct and label stain DNA labeling kit, and then linearized and imaged by Saphyr Whole Genome Imaging Instrument.
Related technologies: Genome mapping
Brand profile
A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.
More info at:
www.bionanogenomics.com
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