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xCELLigence system: rapid and sensitive, ideal for infectious viral assays.

Acea Biosciences

Mar 30, 2020

As the public health threat from COVID-19 and future emergent viruses continue to persist, the rapid, sensitive, and...

Genotype-targeted local therapy of glioma

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Lower-grade gliomas are often characterized by mutations in metabolism-related genes isocitrate dehydrogenase 1 (IDH1)...

Cytek spectral cytometers: 21 color panels with just 2 lasers

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Until recently, developing multicolor fluorescence-based flow cytometry assays on a two laser system has been limited...

Cancer cells resist mechanical destruction in the circulation via RhoA-myosin II axis

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Tumors may generate millions of Circulating tumor cells per day, but seminal work in cancer biology has established the...

Mar 31, 2020

IncuCyte live cell analysis system for 3D Organoids discovery

Sartorius

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Live-Cell Analysis has revolutionized numerous studies, with a wide selection of applications namely 3D Tumour Spheroid...

Webinar recording: Ex vivo microangioCT, advances in microvascular imaging

Bruker Biospin

Mar 16, 2020

A new technique called microangioCT imaging is being used with a novel polymerizing contrast agent that enables 3D...

Single Cell Sequencing sample preparation without centrifugation

Curiox

Mar 10, 2020

Single-cell genomics is rapidly growing. Nature Methods named multimodal omics the method of the year for 2019. And as...

Mar 31, 2020

Introducing Amnis CellStream - Ultra-high sensitivity and flexibility

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The new CellStream Benchtop flow cytometer delivers unparalleled sensitivity and flexibility for cell and particle...

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Cancer immunotherapy: Macrophage-mediated phagocytosis

Oct 27, 2016

In a recent study the secreted glycoprotein thrombospondin 1 (TSP1) was shown to be a positive modulator of innate antitumor immunity by increasing M1 macrophage recruitment and stimulating reactive oxygen species (ROS)-mediated tumor cell killing. These conclusions were drawn, in part, by using xCELLigence RTCA impedance monitoring to evaluate the effect of TSP1 on macrophage/ monocyte activity when co-cultured with MDA-MB-231 breast adenocarcinoma target cells. The % cytolysis data clearly indicate that the tumoricidal activity of both differentiated U937 human monocytes and activated ANA-1 murine macrophages  are enhanced in the presence of TSP1.

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Riccardo Pasculli

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Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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Located inside a tissue culture incubator, the RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement

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Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

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