Accelerate to discover

Back to filter

Related topics

Real-time and quantitative analysis of Macrophage Phagocytosis with RTCA eSight

Agilent technologies

Feb 23, 2024

The eSight is currently the only instrument that interrogates cell health and behavior using cellular
impedance
...

Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System

Luxonus

Feb 21, 2024

In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...

Therapeutic effects of mesenchymal stem cells in myocardial infarction

S-Sharp

Feb 19, 2024

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem...

Whole-slide biomarker quantitation in 82-patient NSCLC cohort study of acquired resistance to PD-(L)

RareCyte

Feb 7, 2024

Samples from 82 patients with NSCLC and matched pre- and post-ICI biopsies were subjected to genomic profiling and to...

Mar 2, 2024

Introducing The Cytek Orion: Reagent Cocktail Preparation System

Cytek Biosciences

Jan 29, 2024

Cytek is proud to announce the Cytek Orion reagent cocktail preparation system. The Cytek Orion system allows for...

Evaluation with BLI of synthetic immune checkpoint engagers in allogenic mice

Spectral Instruments Imaging

Jan 17, 2024

Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity

Application of focal X-ray irradiation in canaries

Precision X-Ray

Jan 15, 2024

Effects of the depletion of neural progenitors by focal X-ray irradiation on song production and perception in canaries

Mar 2, 2024

Radiation planning for image guided preclinical radiotherapy

Precision X-Ray

Jan 12, 2024

Doctoral Thesis, Stefan van Hoof, Maastricht University 2019

Show all topics (10)

Cancer immunotherapy: Macrophage-mediated phagocytosis

Oct 27, 2016

In a recent study the secreted glycoprotein thrombospondin 1 (TSP1) was shown to be a positive modulator of innate antitumor immunity by increasing M1 macrophage recruitment and stimulating reactive oxygen species (ROS)-mediated tumor cell killing. These conclusions were drawn, in part, by using xCELLigence RTCA impedance monitoring to evaluate the effect of TSP1 on macrophage/ monocyte activity when co-cultured with MDA-MB-231 breast adenocarcinoma target cells. The % cytolysis data clearly indicate that the tumoricidal activity of both differentiated U937 human monocytes and activated ANA-1 murine macrophages  are enhanced in the presence of TSP1.

Read more

Scientific paper
Application
Product news

Related technologies: Real-time, label free cell analysis

Get more info

Riccardo Pasculli

Head of application support

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

Agilent technologies

Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

Related products

Located inside a tissue culture incubator, the RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

show detail

Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

show detail

Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement

show detail

Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey