Accelerate to Discover

Back to filter

Related topics

B fibers are the best predictors of cardiac activity during Vagus nerve stimulation

VisualSonics FujiFilm

Jul 17, 2018

Vagus nerve stimulation (VNS) is a promising therapy for many neurologic and psychiatric conditions. However,...

New technologies to uncover the molecular basis of disorders of sex development

BioNano Genomics

Jul 13, 2018

Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel...

δT cells and CD8+ T cells targeting of breast cancer cells

Etaluma

Jul 11, 2018

Cancer stem cells (CSCs) are a large cause of metastasis in breast cancer. They are also very resistent to any...

Incucyte system used for generating single-cell-derived cancer-associated fibroblast clones

Sartorius

Jul 9, 2018

Single-cell-derived cancer-associated fibroblast (CAFs) were produced using Incucyte. These cells were used to help...

Jul 18, 2018

Real-time study of platelet formation under sheer-flow with Lumascope

Etaluma

Jun 18, 2018

Platelet formation was observed with Lumascope microscope in a uniform-sheer-flow biorector. Videos of the formation...

Early fetal sex determination using micro-volume of maternal plasma

BJS Biotechnologies

Jun 16, 2018

 A qPCR-based assay, SneakPeek Early Gender Test (Gateway Genomics) has been developed to determine fetal sex as early...

3R Compliant drug development studies

Bruker Biospin

Jun 8, 2018

In preclinical imaging, magnetic resonance imaging (MRI) can be an attractive alternative to researchers who have...

Jul 18, 2018

Kinase study of cytotoxicity voted paper of the year.

Acea Biosciences

Jun 6, 2018

Society of Toxicology voted a xCELLigence based paper the Paper of the Year. The study of cytotoxicity was done using...

Show all topics (10)

Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy

Sep 12, 2017

Using standard cell lines, although attractive, can lead to unexpected results and probably to important differences when investigating a drug in primary cell lines isolated from patients. The opportunity to use cells of human origin may improve the predictive value of assays in drug testing and came hand in hand with the development of innovative real-time monitoring of cellular behaviour.

xCELLigence real time cell analyser offers a label-free non-invasive manner long-term recording of cellular signals. Considering all this aspects, the aim of our research was to evaluate the impedance of the primary melanocytes isolated from excised tumours that were confirmed as cutaneous melanoma. Primary cell cultures were used for establishing the efficacy pattern of a standard cytostatic, dacarbazine.
Our goal stands for obtaining a work flow for validating specific drug’s efficacy in individual tumour cells as a mean to personalize therapy in melanoma.

Read more

Scientific paper

Related technologies: Real-time, Label Free Cell Analysis

Get more info

Riccardo Pasculli

Field Application Specialist

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

Related products

The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

show detail

Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

show detail

Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement

show detail

Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey