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Cancer samples are just too complex for low coverage whole genome sequencing. Complex rearrangements, tumor heterogeneity and unsequenceable repetitive regions of the genome present additional challenges for short and long read sequencing technologies. Bionano genome imaging finds structural variations larger than 500 bp, unbiased and genome-wide, with the highest sensitivities and the lowest false positive rates, down to 1% variant allele fraction. Bionano consolidates karyotyping, FISH and aCGH in a single automated assay that can be analyzed with just a few clicks.
Related technologies: Genome mapping
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A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.
More info at:
www.bionanogenomics.com
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