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Detect structural variants at 1% allele fraction: Dive deeper into heterogeneous cancer samples

May 22, 2020

Cancer samples are just too complex for low coverage whole genome sequencing. Complex rearrangements, tumor heterogeneity and unsequenceable repetitive regions of the genome present additional challenges for short and long read sequencing technologies. Bionano genome imaging finds structural variations larger than 500 bp, unbiased and genome-wide, with the highest sensitivities and the lowest false positive rates, down to 1% variant allele fraction. Bionano consolidates karyotyping, FISH and aCGH in a single automated assay that can be analyzed with just a few clicks.

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BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

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Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

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Saphyr provides rapid, high-throughput, long-range genome mapping with unmatched structural variation discovery capabilities

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