Accelerate to discover
Related topics
STAT Protein Phosphorylation in CD4+ T Cells using the CellStream flow cytometer
Jan 21, 2021
Cytokine-induced protein phosphorylation is a key cell signaling event within the immune system that modulates diverse...
Introducing Cytek cFluor, 14 Colors Immunoprofiling Kit
Jan 19, 2021
Cytek cFluor Immunoprofiling Kit allows for the identification of helper T cells, cytotoxic T cells, B cells, NK cells...
A Glimpse on physiological monitoring for the in vivo SKYSCAN Systems
Jan 14, 2021
This past year has proven once again that in vivo imaging is an important aspect in the microCT world. For longitudinal...
Cytek full Spectrum flow Cytometry webinar: Part II – panel design and troubleshooting
Jan 11, 2021
In this session, we will continue to look at full spectrum flow cytometry and look at considerations for fluorescence...
CQ1 webinar : optimizing high-content imaging of 3D models for drug discovery
Jan 7, 2021
In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their...
IncuCyte for in-vitro analysis of SARS-CoV-2 vaccine candidate
Jan 4, 2021
Watch this video to learn how researcher at Humane Genomics are utilizing the Incucyte platform for the in-vitro...
Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice
Dec 28, 2020
Radio-active sources have been used routinely for the preconditioning in humanized mouse models, but safety issues have...
EV imaging series: Using ONI super-resolution to characterize single-EVs
Dec 23, 2020
To date, researchers commonly use flow-based characterization methods, fluorescence imaging techniques and electron...
Aug 7, 2018
LSD1 is a flavin adenine dinucleotide (FAD)-dependent homolog of the amine oxidase family and there was recently brought attention to it as a potential therapeutic target. The interest came from an observation of unusually high expression of LSD1 in certain types of poor-prognosis cancers. It was previously thought that LSD1 removes monomethyl and dymethyl histone marks. However, recently it was showed that it interacts with multiple transcripton factor. This raised a possibility of other drugs being used.
New inhibitor ORY-1001 was succesfully tested on LSD1 and blast cell differentioation was observed. The flow cytometric testing on this experiment was done with Novocyte. ORY-1001 disrupts the protein interaction between LSD1 and GFI1.
Related technologies: Conventional flow cytometry
Get more info
Brand profile
Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.
More info at:
www.aceabio.com
BioFocus newsletter
Register to receive Brand new technology development, Important product updates, Interesting scientific events and more!
BioTech a.s. © 2014
Designed & developed by imagineit
Technologies
