Accelerate to discover
Related topics
Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice
Dec 28, 2020
Radio-active sources have been used routinely for the preconditioning in humanized mouse models, but safety issues have...
EV imaging series: Using ONI super-resolution to characterize single-EVs
Dec 23, 2020
To date, researchers commonly use flow-based characterization methods, fluorescence imaging techniques and electron...
Don’t Let Waste Anesthetic Gases Harm You!
Dec 21, 2020
Many projects have been devoted to the study of the correlation between anesthetics and Alzheimer’s disease....
Advances in Leukemia research using shear flow and Bioflux system
Dec 10, 2020
Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune...
Do you have our CellRad benchtop irradiator? It’s the only one on the market!
Dec 8, 2020
The CellRad is a smaller, simpler, safer, and more cost effective alternative to radioisotope or high-powered X-ray...
Dosimetric characterization of an X-ray irradiator for use with cells
Dec 4, 2020
This study aims to characterize an X-ray irradiator for use with cells using its internal parallel-plate ionization...
Modeling multiple myeloma-Bone Marrow interactions using Synthecon rotating-wall vessels
Dec 2, 2020
Multiple myeloma develops primarily inside the bone marrow microenvironment, that confers pro-survival signals and drug...
Bruker webinar: Ear evolution in fossil mammals
Nov 27, 2020
Hearing is just one of the functions aside of providing balance. Even juveniles obtain a fully developed ear region...
Mar 26, 2020
Aggressive neurosurgical resection to achieve sustained local control is essential for prolonging survival in patients with lower-grade glioma. However, progression in many of these patients is characterized by local regrowth. Most lower-grade gliomas harbor isocitrate dehydrogenase 1 (IDH1) or IDH2 mutations, which sensitize to metabolism-altering agents. To improve local control of IDH mutant gliomas while avoiding systemic toxicity associated with metabolic therapies, a precision intraoperative treatment was developer, that couples a rapid multiplexed genotyping tool with a sustained release microparticle (MP) drug delivery system containing an IDH-directed nicotinamide phosphoribosyltransferase (NAMPT) inhibitor (GMX-1778). GMX-1778 MPs showed mutant IDH genotype-specific toxicity in vitro and in vivo, inducing regression of orthotopic IDH mutant glioma murine models.
Related technologies: Fluorescence, luminescence, X-ray, radiographic imaging
Get more info
Brand profile
Spectral Instruments Imaging manufactures instruments for preclinical optical (bioluminescent, fluorescent) and X-ray imaging.
More info at:
https://spectralinvivo.com/
BioFocus newsletter
Register to receive Brand new technology development, Important product updates, Interesting scientific events and more!
BioTech a.s. © 2014
Designed & developed by imagineit
Technologies
