Accelerate to discover

Back to filter

Related topics

Hypoxia in the Tumor Immune Microenvironment (TIME)

Bruker Biospin

Jun 6, 2024

Thursday, 11 July 2024, 16:00 CET | 10:00 EST
Zaver M. Bhujwalla, PhD...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

Jun 5, 2024

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

Bruker Biospin

Jun 4, 2024

MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...

Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics

Spectral Instruments Imaging

Jun 3, 2024

Disha Moholkar of University of Louisville's Gupta Lab
Tuesday, June 11, 2024, 6:30 PM
...

Jun 24, 2024

Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

Cell Microsystems

May 27, 2024

Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...

High-frequency Ultrasound System For Preclinical Imaging

S-Sharp

May 13, 2024

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

“Range+T “ for Tight Sizing of HMW Libraries

Sage Science

May 10, 2024

We decided to do a deep dive into Range+T to get a better handle the method, and to develop best practices for using...

Jun 24, 2024

April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies

IVIM Technology

May 8, 2024

Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded...

Show all topics (10)

In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

Apr 26, 2019

Since cobalt contributes to physiological and pathological processes, the underlying mechanism of the correlation between its biological occurrence/trafficking and healthy and disease status is still unclear. Therefore, the detection of cobalt in the environmental system and living organs has drawn intensive attention. In this content, a number of techniques are known to be widely applied in cobalt analysis, such as HPLC, flame atomic absorption spectroscopy (FAAS), spectrophotography, and adsorptive voltammetric and inductively coupled plasma atomic emission spectrometry (ICP - AES). However, the bulk traditional analysis methods typically require sophisticated sample preparation procedures, highly trained individuals, and costly instruments. More importantly, none of them are compatible with living organisms.

Among these collections, the optical probes, due to good sensitivity and bioavailability, construct a great figure as a valuable chemical tool to effectively monitor and track analytes of interest in the biological specimens/living organisms and therefore are extremely beneficial for the broader scientific community. To date, some fluorescent and colorimetric probes have been reported for the detection of cobalt, and none of them has been applied to in vivo imaging. Therefore, there is an urgent demand on developing novel strategies for monitoring cobalt flux, in particular, in the whole animal.

Do you want to learn more? Read this interesting article!

Scientific paper
Application

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 210 323 421

Send Message

Brand profile

Spectral Instruments Imaging

Spectral Instruments Imaging manufactures instruments for preclinical optical (bioluminescent, fluorescent) and X-ray imaging.

Related products

System for individual researchers and smaller specialist teams to conduct optical imaging studies in disease model progression, response to therapy, and cell migration in-vivo.

show detail

The Ami HT and Ami HTX (includes X-Ray imaging) optical imaging systems establish a new, high throughput benchmark for in vivo imaging suitable for specialist researchers and small teams.

show detail

The Lago and X‐Ray capable Lago X optical imaging systems provide a powerful and flexible in-vivo imaging capability suitable for imaging cores, specialist researchers and small teams, delivering an unmatched 10 mouse capacity across BLI, FLI and X‐Ray.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey