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IncuCyte live-cell analysis sytem progress COVID 19 vaccine research

Jul 20, 2020

We want to share exciting news: Lab results show that scientists made our vaccine as designed using IncuCyte live-cell analysis system. In our previous post, we disclosed a design of a potential vaccine for COVID-19 based on VSV. In a subsequent post, we have also shared quite a bit of scientific background on why we believe it should work. With this news, we want to share an update on our work in the lab.

The physical outside of the virus SARS-CoV-2 is characterized by the spike protein. It is the spike protein that enables the virus to infect cells. How does it do that? The spike protein matches with the so-called ACE2 receptor on cells. You could say that the ACE2 receptors are the lock and the spike protein is the key. Cells that have the ACE2 receptor can be infected by a virus with the spike protein. (FYI human lung cells have ACE2 receptors). By putting our vaccine virus together with cells that have the ACE2 receptor we can see if they can infect them. And that is exactly what we have shown in the lab. See the video below.

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Sartorius

Essen BioScience (part of Sartorius), is a team of engineers and biologists with deep expertise in cell-based assays. They invent, manufacture, supply and support cell-based assay instrumentation, reagents and protocols.

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High throughput, real-time and automated measurements of live-cell activity, inside your incubator

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