Preparative electrophoresis systems for targeted size selection of biomolecules.
Automated microscopy and image analysis
Real-time, label free cell analysis
Nano and micro particle analysis
Accelerate to discover
Back to filter
Show all topics (10)
Related topics
Standardize tumor sample preparation and reduce background with Curiox laminar wash system
Aug 10, 2022
Laminar Wash technology offers a gentle alternative that can improve yield and data quality, particularly of rare cell...
Developing a 43 color panel on Cytek Aurora using Laminar Wash for sample prep
Aug 2, 2022
Successfully executing a 43 color panel is a technically demanding task. One that is made more difficult when there are...
Intoducing spheroOne: Automated sorting and isolation of single spheroids and organoids
Jun 21, 2022
spheroONE is an innovative single large-particle sorter and dispenser which revolutionizes 3D cellular models handling....
Outstanding post-sort sample recovery on the WOLF Cell Sorter
Jun 14, 2022
The new WOLF G2 instrument has significantly expanded the capabilities of gentle benchtop microfluidic cell sorting...
Incucyte AI module: Advanced Label-Free Classification Analysis
Jun 6, 2022
Monitor adherent cell morphology changes objectively to determine live/dead cell counts or classify cells based on...
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters
Jun 3, 2022
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine...
An experimental strategy for preparing circular ssDNA virus genomes for next-generation sequencing
Jun 1, 2022
Recent article from February 2022 shoes how size selection improved viral read mapping by over 90% for begomoviruses.
Intoducing cellenONE: The revolutionary Single Cell isolator
May 25, 2022
A revolutionary platform based on sciDROP PICO precision dispensing technology and coupled with advanced image...
Intact DNA purified from flow-sorted nuclei unlocks the potential of next-generation genome mapping
Jul 20, 2018
Scientists from Wageningen University & Research and other institutions presented technical challenges of obtaining sufficient high molecular weight (HMW) nuclear DNA due to cell walls which are difficult to disrupt. The obtained nuclei are embedded into agarose plugs for processing and isolating uncontaminated HMW DNA, which is a prerequisite for nanochannel-based next-generation optical mapping strategies.
They described important improvements for obtaining HMW DNA that they tested on Solanum crops and wild relatives. Flow sorted nuclei were embedded in agarose plugs and HMW DNA was purified with proteinase K and RNAse A and then isolated. Pulsed-field gel electrophoresis (PFGE) was used for DNA quality control. HMW DNA was subsequently labeled and analyzed on the Irys platform. Optical mapping (OM) data were then processed for de novo OM and hybrid assemblies.
Related technologies: Targeted DNA/protein size collection
Get more info
Brand profile
