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Imaging Performance of a multimodal module to enhance preclinical irradiator capabilities

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Upgrading an existing irradiator with such a multi-modal imaging device is a reasonable investment in laboratories...

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The goal of breast cancer surgery is to remove all of the cancer with a minimum of normal tissue, but absence of full...

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Immunophenotyping Extracellular Vesicles using Amnis CellStream

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Four-week individual caging of male ICR mice alters body composition without change in body mass

MEDIKORS

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Could individual caging affect the physical composition of outbred mice? To investigate this, dual X-ray absorptiometry...

Detect structural variants at 1% allele fraction: Dive deeper into heterogeneous cancer samples

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To get a complete picture of highly rearranged cancer genomes in heterogeneous samples, use Bionano genome imaging...

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Insulin receptor substrate 1 is a substrate of the Pim protein kinases

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The goal of these studies was to identify Pim substrate(s) that could help define the pathway regulated by these...

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Mechanical signalling regulates virulence in pathogenic Escherichia coli

Mar 13, 2017

Although the factors involved in colonization and disease are well characterized, how EHEC regulates its expression in response to a host encounter is not well understood. The authors report that EHEC perceives attachment to host cells as a mechanical cue that leads to expression of LEE-encoded virulence genes.The data suggest that, in addition to a range of chemical environmental signals, EHEC is capable of sensing and responding to mechanical cues to adapt to its host’s physiology.’ While this work was performed at the University of Birmingham, Dr. Krachler is currently an Associate Professor in the department of Microbiology and Molecular Genetics at UT Health, University of Texas. A long-term goal of this type of research is the reduction of deadly infection by preventing bacterial attachment to host tissues.

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Related technologies: Cell interaction studies

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