Accelerate to Discover

Back to filter

Related topics

NovoCyte Quanteon - when exceptional performance meets simplicity

Acea Biosciences

Jun 21, 2018

NovoCyte Quanteon system is the answer for growing demands in modern flow-cytometry assays. With its four lasers (405,...

Method to quantify local force distribution within biomolecular systems

LUMICKS

May 24, 2018

The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA...

Bionano fall user workshop

BioNano Genomics

May 23, 2018

We are happy to announce the Bionano Genomics’ 2018 user workshop taking place in San Diego on October 15-16,...

AVATAR Improves transfection efficiency with high viability

Xcell Biosciences

May 9, 2018

AVATAR lets you create any cell type even novel ones, with efficient transfection that improves reprogramming rates...

Jun 21, 2018

Single-molecule optical mapping enables accurate molecular diagnosis of FSHD

BioNano Genomics

May 3, 2018

This week team from Children’s Hospital of Philadelphia, GrandOmics and three Chinese universities demonstrated that...

Solved with Bionano: The Swedish mystery of the missing reference sequence

BioNano Genomics

Apr 27, 2018

Team from Uppsala University in Sweden used long-read sequencing and Bionano mapping to de novo assemble two Swedish...

Dynamic PET imaging and special focus in cardiac kinetic analysis

Bruker Biospin

Apr 25, 2018

PET has been shown to outperform SPECT in dynamic imaging like myocardial perfusion imaging due to the true...

Jun 21, 2018

Optical methylation mapping made simple

BioNano Genomics

Apr 24, 2018

Reduced representation optical methylation mapping in combination with Bionano genome mapping technology provides a...

Show all topics (10)

New range of circulating tumor cell recovery kits

Mar 15, 2016

Two kits have been launched for enhanced CTC isolation and recovery that are designed to work exclusively with the IsoFlux Liquid Biopsy system. The new kits include the Enhanced Recovery Kit and the EMT Kit. The Enhanced Recovery kit adds EGFR to the traditional EpCAM antibody, and the EMT kit includes EpCAM, EGFR, and two proprietary mesenchymal phenotype antibodies.

The IsoFlux System uses blood to perform a real-time “liquid biopsy” of the patient’s cancer using the recovered CTCs. The high efficiency and high purity of the recovered cells allows for the use of highly multiplexed analyses such as next-generation sequencing (NGS) for cancer mutational profiling. Screening for a broad range of cancer biomarkers via NGS will help guide treatment decisions using an emerging class of precision cancer therapies. The introduction of the new CTC kits increases the recovery efficiency of CTCs, further improving the IsoFlux system’s industry-leading sensitivity.

According to Fluxion’s CTO, Dr. Cristian Ionescu-Zanetti, the new kits provide significant gains in cell recovery and open new avenues in clinical research. “It is well known that EpCAM expression levels vary greatly across cancer types and within cancer cell populations. This can limit the recovery efficiency in very low-expressing cancer types, such as lung and pancreatic cancers. Although the IsoFlux system’s high-sensitivity microfluidic cell recovery performs well on these low expressers when targeting EpCAM, the new kits provide a higher level of performance while enabling recovery of a wider spectrum of cell types. The EMT kit is the first commercially available that targets the mesenchymal cell phenotype for CTCs that have undergone EMT, considered to be a potential contributor to metastasis.”

The Enhanced Recovery Kit and EMT Kit are already available and can be used on all existing IsoFlux systems without modification.

Product news

Related technologies: CTC´s and Rare Cells Analysis

Brand profile

Fluxion Biosciences

With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.

Related products

The IsoFlux System is a benchtop instrument designed to isolate the    CTC´s and enrich rare cell populations

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey