Accelerate to discover

Back to filter

Related topics

IncuCyte white paper: live-cell analysis for Neuroscientists

Sartorius

Mar 20, 2019

Stem cell technologies using iPSCs allow researchers to create differentiated neurons and support cells to study human...

Precision CellRad

Precision X-Ray

Feb 15, 2019

The CellRad system allows you to irradiate cells in your lab without compromising sterility or security. A smaller,...

Etaluma can now offer integrated tablet for LS460/560/620 scopes

Etaluma

Jan 25, 2019

Based on the customer requests of tablet mount configuration for sterile picking in the hood, Etaluma can now offer the...

Spectral data analysis webinar recording - Cytek flow cytometer and De Novo Software

Cytek Biosciences

Jan 17, 2019

Cytek Biosciences and De Novo Software are proud to announce a collaboration that allows you to work with your spectral...

Mar 21, 2019

Cytek Aurora spectral flow cytometer - say hello to a new reality

Cytek Biosciences

Jan 7, 2019

A prodigy that takes flow cytometry to the next level of performance and flexibility. With up to four lasers, three...

ACEA Biosciences launch xCELLigence RTCA software Pro for immunotherapy applications

Acea Biosciences

Dec 28, 2018

RTCA Software Pro is an integrated software package for running and analyzing real time cell analysis data from...

IncuCyte neuronal activity assay

Sartorius

Nov 13, 2018

The generation and maturation of neuronal networks are necessary characteristics of neurogenesis, providing...

Mar 21, 2019

IZON qEV - Isolate your exosomes in just 15 minutes

IZON

Oct 25, 2018

Extracellular  vesicles  (EVs)  are  prevalent  in biological  fluids  and  are  of  great  interest  to researchers ...

Show all topics (10)

New range of circulating tumor cell recovery kits

Mar 15, 2016

Two kits have been launched for enhanced CTC isolation and recovery that are designed to work exclusively with the IsoFlux Liquid Biopsy system. The new kits include the Enhanced Recovery Kit and the EMT Kit. The Enhanced Recovery kit adds EGFR to the traditional EpCAM antibody, and the EMT kit includes EpCAM, EGFR, and two proprietary mesenchymal phenotype antibodies.

The IsoFlux System uses blood to perform a real-time “liquid biopsy” of the patient’s cancer using the recovered CTCs. The high efficiency and high purity of the recovered cells allows for the use of highly multiplexed analyses such as next-generation sequencing (NGS) for cancer mutational profiling. Screening for a broad range of cancer biomarkers via NGS will help guide treatment decisions using an emerging class of precision cancer therapies. The introduction of the new CTC kits increases the recovery efficiency of CTCs, further improving the IsoFlux system’s industry-leading sensitivity.

According to Fluxion’s CTO, Dr. Cristian Ionescu-Zanetti, the new kits provide significant gains in cell recovery and open new avenues in clinical research. “It is well known that EpCAM expression levels vary greatly across cancer types and within cancer cell populations. This can limit the recovery efficiency in very low-expressing cancer types, such as lung and pancreatic cancers. Although the IsoFlux system’s high-sensitivity microfluidic cell recovery performs well on these low expressers when targeting EpCAM, the new kits provide a higher level of performance while enabling recovery of a wider spectrum of cell types. The EMT kit is the first commercially available that targets the mesenchymal cell phenotype for CTCs that have undergone EMT, considered to be a potential contributor to metastasis.”

The Enhanced Recovery Kit and EMT Kit are already available and can be used on all existing IsoFlux systems without modification.

Product news

Related technologies: CTC´s and rare cells analysis

Brand profile

Fluxion Biosciences

With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.

Related products

The IsoFlux System is a benchtop instrument designed to isolate the    CTC´s and enrich rare cell populations

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey