Accelerate to discover
Related topics
Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice
Dec 28, 2020
Radio-active sources have been used routinely for the preconditioning in humanized mouse models, but safety issues have...
EV imaging series: Using ONI super-resolution to characterize single-EVs
Dec 23, 2020
To date, researchers commonly use flow-based characterization methods, fluorescence imaging techniques and electron...
Don’t Let Waste Anesthetic Gases Harm You!
Dec 21, 2020
Many projects have been devoted to the study of the correlation between anesthetics and Alzheimer’s disease....
Advances in Leukemia research using shear flow and Bioflux system
Dec 10, 2020
Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune...
Do you have our CellRad benchtop irradiator? It’s the only one on the market!
Dec 8, 2020
The CellRad is a smaller, simpler, safer, and more cost effective alternative to radioisotope or high-powered X-ray...
Dosimetric characterization of an X-ray irradiator for use with cells
Dec 4, 2020
This study aims to characterize an X-ray irradiator for use with cells using its internal parallel-plate ionization...
Modeling multiple myeloma-Bone Marrow interactions using Synthecon rotating-wall vessels
Dec 2, 2020
Multiple myeloma develops primarily inside the bone marrow microenvironment, that confers pro-survival signals and drug...
Bruker webinar: Ear evolution in fossil mammals
Nov 27, 2020
Hearing is just one of the functions aside of providing balance. Even juveniles obtain a fully developed ear region...
Aug 26, 2019
The “gold standard” used to measure platelet function is light transmission aggregometry (LTA) where platelet aggregation is measured by changes in light transmission on a spectrometer. However, LTA is cumbersome and results vary with platelet count, making it unsuitable for patients with thrombocytopenia. In addition, LTA requires a large volume of blood while investigating only one aspect of platelet function. Therefore, improved methods to measure platelet function are needed.
Flow cytometry has already been widely used to diagnose several platelet disorders and recently, techniques have been developed to measure platelet function. Measuring platelet activity by flow cytometry offers several advantages over LTA in that only small amount of blood volumes are needed, whole blood can be used, and results are independent of platelet count. Furthermore, the possibility of ready-made tubes with fixative would extend the time between blood collection and analysis, crucial for field testing. In this application note, we have measured platelet function in two ways: expression of CD62P and by frequency of platelet-leukocyte aggregates.
Related technologies: Conventional flow cytometry
Get more info
Brand profile
ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.
More info at:
www.aceabio.com
BioFocus newsletter
Register to receive Brand new technology development, Important product updates, Interesting scientific events and more!
BioTech a.s. © 2014
Designed & developed by imagineit
Technologies
