Spectral Instruments Imaging manufactures instruments for preclinical optical (bioluminescent, fluorescent) and X-ray imaging.
Automated microscopy and image analysis
Real-time, label free cell analysis
Nano and micro particle analysis
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Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts
Jan 30, 2019
CF33 caused rapid killing of six pancreatic cancer cells lines in vitro, releasing damage-associated molecular patterns, and regression of PANC-1 injected and non-injected distant xenografts in vivo after a single low intratumoral dose of 103 plaque-forming units. Using luciferase imaging, CF33 was noted to preferentially replicate in tumors which corresponds to the low viral titers found in solid organs.
Related technologies: Fluorescence, luminescence, X-ray, radiographic imaging
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