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Webinar recording: Analysis of extracellular vesicles by AMNIS imaging flow cytometer

Luminex

Nov 4, 2019

Although conventional flow cytometry is limited to measure small particles down to approximately 300 nm – 500 nm, an...

Targeted mitochondrial DNA extraction and enrichment using the SageHLS

Sage Science

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Sage Science introduced a novel approach for enriching mitochondrial DNA for sequence analysis without PCR or gradient...

Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer at a single low dose

Spectral Instruments Imaging

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Pancreatic ductal adenocarcinoma (PDAC) has been increasing by 0.5% per year in the United States. This study describes...

New code dedicated to esophageal procedures with Confocal Laser Endomicroscopy

Mauna Kea Technologies

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Announcement of the creation of a new specific procedural code to be added to the Common Classification of Medical...

Nov 11, 2019

VisualSonics AutoLV

VisualSonics FujiFilm

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VisualSonics AutoLV allow functional and anatomical analysis of the left ventricle in one click using the power of...

New study resolves helicase dynamics and interactions during DNA replication using C-Trap

LUMICKS

Aug 30, 2019

Researchers from Rockefeller University used a C-Trap optical tweezers – fluorescence microscopy system to observe the...

Low-dose maging in a new preclinical total-body PET/CT scanner

Bruker Biospin

Aug 28, 2019

Ionizing radiation constitutes a health risk to imaging scientists and study animals. Both PET and CT produce ionizing...

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Novel methods to analyze platelet activation with the NovoCyte flow cytometer

Acea Biosciences

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Platelets are of large importance in medicine both for their essential role in hemostasis and thrombosis, as well as...

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Optical advances – the latest developments in Preclinical imaging

Aug 5, 2016

Preclinical in vivo molecular imaging is widely regarded as a key tool within the drug discovery and development pipeline, giving researchers clear visibility of cellular changes at a molecular level. Techniques – or modalities – such as optical, PET and SPECT imaging provide high specificity and wide applicability, as well as the ability to monitor several molecular events and identify key molecular markers. The result is a deeper understanding of disease progression, and the mode of action and pharmacokinetics of potential therapeutics.

If we consider small animal optical imaging systems specifically, these now enable researchers to combine a number of imaging modalities using the same instrument, thereby paving the way for a better understanding of physiological and disease mechanisms in the preclinical setting. For example, one such system provides five imaging modalities as standard, allowing for co-registration of molecular events with access to bioluminescence, multispectral VIS-NIR fluorescence, unique direct radioisotopic imaging, and Cerenkov radiation. A high speed digital X-ray scanner adds to the functional images with morphological features.

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Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

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Albira combines PET, SPECT and CT imaging in a unique and extremely powerful way

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