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New study resolves helicase dynamics and interactions during DNA replication using C-Trap

LUMICKS

Aug 30, 2019

Researchers from Rockefeller University used a C-Trap optical tweezers – fluorescence microscopy system to observe the...

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Sep 22, 2019

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The BluePippin was used for High Pass DNA size selection prior to library construction. ONT Promethion was used for...

Next-generation cytogenetics is here

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Preclinical cardiac safety assessment using xCELLigence Cardio

Apr 21, 2016

Most of the drugs that have been withdrawn from the market due to cardiotoxicity appear to affect heart function by directly interfering with well-coordinated electrical activity in the heart.The electrical activity of the heart itself results from directional and selective movement of calcium, sodium, and potassium ions across channels in the membrane of cardiomyocytes; this movement couples with the specialized cytoskeleton to produce contraction and the force necessary for the pumping action of the heart. Interfering with this well-orchestrated movement of ions across the cardiomyocyte membrane can lead to electrical arrhythmia that will ultimately affect the excitation/contraction coupling cycle of the heart and may lead to a life-threatening form of ventricular arrhythmia called Torsades de Pointes (TdP).

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Related technologies: Real-time, label free cell analysis

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Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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Cardio Instrument is a high-resolution system for label-free-dual-mode monitoring of cardiomyocyte and cardiotoxicity testing

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The new CardioECR system combines impedance and Multi Electrode Array (MEA) technology with a pacing function

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