Accelerate to discover

Back to filter

Related topics

Webinar : meet the Cytek's new cFluor reagents

Cytek Biosciences

Jan 25, 2021

Cytek Biosciences has already redefined what is possible in flow cytometry. The new Cytek cFluor family of reagents...

STAT Protein Phosphorylation in CD4+ T Cells using the CellStream flow cytometer

Luminex

Jan 21, 2021

Cytokine-induced protein phosphorylation is a key cell signaling event within the immune system that modulates diverse...

Introducing Cytek cFluor, 14 Colors Immunoprofiling Kit

Cytek Biosciences

Jan 19, 2021

Cytek cFluor Immunoprofiling Kit allows for the identification of helper T cells, cytotoxic T cells, B cells, NK cells...

A Glimpse on physiological monitoring for the in vivo SKYSCAN Systems

Bruker Biospin

Jan 14, 2021

This past year has proven once again that in vivo imaging is an important aspect in the microCT world. For longitudinal...

Jan 27, 2021

Cytek full Spectrum flow Cytometry webinar: Part II – panel design and troubleshooting

Cytek Biosciences

Jan 11, 2021

In this session, we will continue to look at full spectrum flow cytometry and look at considerations for fluorescence...

CQ1 webinar : optimizing high-content imaging of 3D models for drug discovery

Yokogawa

Jan 7, 2021

In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their...

IncuCyte for in-vitro analysis of SARS-CoV-2 vaccine candidate

Sartorius

Jan 4, 2021

Watch this video to learn how researcher at Humane Genomics are utilizing the Incucyte platform for the in-vitro...

Jan 27, 2021

Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice

Precision X-Ray

Dec 28, 2020

Radio-active sources have been used routinely for the preconditioning in humanized mouse models, but safety issues have...

Show all topics (10)

Real-time study of platelet formation under sheer-flow with Lumascope

Jun 18, 2018

Platelets are discoids with the size of about 2-3 µm which are responsible for thrombosis and hemostasis. Today platelet transfusion has wide clinical application in blood clotting and wound healing with over 2 million units of platelets transfused every year in the US alone. However, the need for human donors and short shelf life of five days makes the use complicated. Therefore, novel approaches to generate platelets ex vivo are being researched. A promising approach is deriving platelets from megakaryocytes. But generating a large number of platelets with megakaryocyte stimulation has proved difficult. In this research, a sheer-rate bioreactor was used to stimulate the blood flow in the body to encourage the stimulation. Formation of a high number of platelet-like-particles (PLPs) was observed after this stimulation with Lumascope microscope inside of an incubator. Videos of 6 frames per second were generated in five-minute intervals and further analysed. It was shown that introduction of sheer-flow had an almost immediate effect on the PLP generation. With a six-fold increase of PLP production under single flow. This study shows promising results in understanding the PLP formation and creates a possibility of using these condition in creating ex vivo platelets for clinical use. 

Scientific paper
Application

Brand profile

Etaluma

With a focus on portability, ease of use, high-quality imaging and fast frame-rate, Etaluma developed new concept in simple, affordable, and accessible fluorescence microscopy.

Related products

Lumascope 620 offers a larger sensor and 3-color fluorescence for the most powerful microscope offered anywhere at this price

show detail

Blue, green & red fluorescence and walk-away automation

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey