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Method to quantify local force distribution within biomolecular systems

LUMICKS

May 24, 2018

The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA...

Bionano fall user workshop

BioNano Genomics

May 23, 2018

We are happy to announce the Bionano Genomics’ 2018 user workshop taking place in San Diego on October 15-16,...

AVATAR Improves transfection efficiency with high viability

Xcell Biosciences

May 9, 2018

AVATAR lets you create any cell type even novel ones, with efficient transfection that improves reprogramming rates...

Single-molecule optical mapping enables accurate molecular diagnosis of FSHD

BioNano Genomics

May 3, 2018

This week team from Children’s Hospital of Philadelphia, GrandOmics and three Chinese universities demonstrated that...

May 28, 2018

Solved with Bionano: The Swedish mystery of the missing reference sequence

BioNano Genomics

Apr 27, 2018

Team from Uppsala University in Sweden used long-read sequencing and Bionano mapping to de novo assemble two Swedish...

Dynamic PET imaging and special focus in cardiac kinetic analysis

Bruker Biospin

Apr 25, 2018

PET has been shown to outperform SPECT in dynamic imaging like myocardial perfusion imaging due to the true...

Optical methylation mapping made simple

BioNano Genomics

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Reduced representation optical methylation mapping in combination with Bionano genome mapping technology provides a...

May 28, 2018

Inhibition of T cell receptor signaling mediated Calcium flux in T cells

Apr 23, 2018

Calcium (Ca2+) is an important secondary messenger and a key component of many cell processes. It is an extremely...

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Simultaneous Measurement of Cardiomyocyte Contractility and Electrophysiology

Sep 29, 2015

The xCELLigence RTCA CardioECR System allows for comprehensive evaluation of processes involved in cardiomyocyte excitation-contraction coupling. The included software package is specifically designed to identify and measure adverse compound action on integrated ion channel activity, contractility and longer term viability and thus provides a highly predictive assay system for cardiac risk assessment.

 

The principle of detection for the xCELLigence RTCA CardioECR System is based on impedance and field potential measurements. The interdigitated gold impedance electrodes are interspersed with two field potential electrodes. These electrodes are specially designed for simultaneous measurement of field potential and contractility within each well of the microtiter plate.

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Related technologies: Real-time, Label Free Cell Analysis

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Riccardo Pasculli

Field Application Specialist

Riccardo

Pasculli

+420 731 127 717

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Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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The new CardioECR system combines impedance and Multi Electrode Array (MEA) technology with a pacing function

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