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Outstanding post-sort sample recovery on the WOLF Cell Sorter

NanoCellect

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The new WOLF G2 instrument has significantly expanded the capabilities of gentle benchtop microfluidic cell sorting...

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters

MOLECUBES

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Multi-modal PET drives interdisciplinary preclinical imaging

Bruker Biospin

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Preclinical imaging (PCI) plays a vital role in understanding the biological processes behind disease states at the...

Quantitative 3D Optical Imaging for Lago

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Spectral Instrument Imaging just announced a new, strategic partnership with InVivo Analytics, which enables...

Reduces fMRI-BOLD Response in the Brain

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fMRI studies often involve the electrical stimulation of i.e. the forepaw, detecting where this stimulation is...

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Extensive assessment of Cytokine production on the NovoCyte Penteon flow cytometer

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Cytokines are small molecules essential for immune cell response to activation by pathogens, autoimmunity, or...

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Use of the real time xCelligence system for purposes of medical microbiology

Apr 21, 2016

Celligence impedance-measuring instrument is one of a few commercially available systems of such type. The aim of this work was to estimate xCELLigence suitability for the microbiological tests, including measurement of morphological changes in eukaryotic cells as a result of bacterial toxin activity, measurement of bacterial biofilm formation and impact of antiseptics on the biofilm structure. To test the infuence of bacterial enterotoxin on eukaryotic cell lines, Chinese Hamster Ovary (CHO) cell line and reference strain Escherichia coli ATTC 35401 were used. To investigate instrument ability to measure biofilm formation and impact of antiseptics on its development, Staphylococcus aureus ATTC6538 reference strain was used. The data generated during the experiments indicate excellent ability of xCelligence instrument to detect cytopathic effect caused by bacterial LT endotoxin and to detect staphylococcal biofilm formation.  xCelligence instrument can be used for real-time monitoring of morphological changes in CHO cells treated with bacterial LT enterotoxin and for real-time measurement of staphylococcal biofilm formation in vitro.

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Scientific paper

Related technologies: Real-time, label free cell analysis

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Agilent technologies

Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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Located inside a tissue culture incubator, the RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

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