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Small animal 13C-hyperpolarized MRI

Bruker Biospin

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13C-Hyperpolarized molecules provide a unique signature for molecular processes relevant to a range of disease...

Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts

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Spectral Instruments Imaging

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In this work, a new fluorescence probe, PQI, was developed for monitoring of the HOCl level in biological samples. The...

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Synthecon

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Bruker Biospin

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The ROI shrink‐wrap gives the possibility to automatically generate a region‐of‐interest by adapting to the shape of...

Cellular stress induces erythrocyte assembly and promotes microangiopathy

Fluxion Biosciences

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The need for ultra high field magnetic resonance imaging

Bruker Biospin

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MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...

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Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies

Etaluma

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Accurate labeling of endogenous proteins for advanced light microscopy in living cells remains challenging. Nanobodies...

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Use of the real time xCelligence system for purposes of medical microbiology

Apr 21, 2016

Celligence impedance-measuring instrument is one of a few commercially available systems of such type. The aim of this work was to estimate xCELLigence suitability for the microbiological tests, including measurement of morphological changes in eukaryotic cells as a result of bacterial toxin activity, measurement of bacterial biofilm formation and impact of antiseptics on the biofilm structure. To test the infuence of bacterial enterotoxin on eukaryotic cell lines, Chinese Hamster Ovary (CHO) cell line and reference strain Escherichia coli ATTC 35401 were used. To investigate instrument ability to measure biofilm formation and impact of antiseptics on its development, Staphylococcus aureus ATTC6538 reference strain was used. The data generated during the experiments indicate excellent ability of xCelligence instrument to detect cytopathic effect caused by bacterial LT endotoxin and to detect staphylococcal biofilm formation.  xCelligence instrument can be used for real-time monitoring of morphological changes in CHO cells treated with bacterial LT enterotoxin and for real-time measurement of staphylococcal biofilm formation in vitro.

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Related technologies: Real-time, label free cell analysis

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Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

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