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PET/CT Si78: Versatility in microCT dose, speed, & resolution

Bruker Biospin

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The Bruker PET/CT Si78 now pairs total-body PET and SkyScan microCT technology. This combination offers the advanced...

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Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80-85% cases of lung cancer....

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A large percentage of drugs fail in clinical studies due to cardiac toxicity, such as drug-induced QT...

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The albumin nanoparticles were fabricated using a beta-carotene cross-linker via the Nab technique. These new albumin...

Spectral flow cytometric analysis of loss-of-function mutations in granular cell tumors

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Cell plasticity associated to circulating tumor cells from prostate cancer patients

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Treatment resistance is associated with tumor cells molecular plasticity. In metastatic castration resistant prostate...

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Use of the real time xCelligence system for purposes of medical microbiology

Apr 21, 2016

Celligence impedance-measuring instrument is one of a few commercially available systems of such type. The aim of this work was to estimate xCELLigence suitability for the microbiological tests, including measurement of morphological changes in eukaryotic cells as a result of bacterial toxin activity, measurement of bacterial biofilm formation and impact of antiseptics on the biofilm structure. To test the infuence of bacterial enterotoxin on eukaryotic cell lines, Chinese Hamster Ovary (CHO) cell line and reference strain Escherichia coli ATTC 35401 were used. To investigate instrument ability to measure biofilm formation and impact of antiseptics on its development, Staphylococcus aureus ATTC6538 reference strain was used. The data generated during the experiments indicate excellent ability of xCelligence instrument to detect cytopathic effect caused by bacterial LT endotoxin and to detect staphylococcal biofilm formation.  xCelligence instrument can be used for real-time monitoring of morphological changes in CHO cells treated with bacterial LT enterotoxin and for real-time measurement of staphylococcal biofilm formation in vitro.

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Scientific paper

Related technologies: Real-time, label free cell analysis

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Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

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