As the public health threat from COVID-19 and future emergent viruses continue to persist, developing novel methods to screen antivirals will be important for creating broad-spectrum anti-viral drugs and vaccines. The accurate measurement of viral activity plays an essential role for viral vaccine development and infectious disease studies. When infected with a virus, host cells often display changes that are collectively referred to as a cytopathic effect (CPE) which include cell shrinkage or enlargement, deterioration/lysis, cell fusion, and the formation of inclusion bodies.
Download the Vaccine & Virology Handbook to discover a more accurate method to characterize viral activity. Applications include viral titer determination, detection and quantification of neutralizing antibodies, studying anti-viral drugs, testing virucides, oncolytic viruses, and assessing virus quality or fitness.
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