Synthecon

Synthecon, Incorporated is a biotechnology company that specializes in the design and manufacture of 3D cell culture systems. Synthecon’s rotating bioreactors have applications in various fields of cell culture and tissue engineering and stem cell culture for regenerative medicine. Synthecon’s bioreactors have been recognized by over 500 peer-reviewed scientific publications as a superior technology for growing 3D tissue analogs.

Synthecon has been the leading 3D bioreactor cell culture company in the biotechnology industry since 1990 originally based on a NASA-developed patent for the Rotating Wall Wessel (RWV) bioreactor. Synthecon continues to be a research-driven, innovative firm, striving to meet the needs of researchers who are dedicated to curing serious illnesses and disease conditions.

RCCS features:

• Ability to co-culture multiple cell types in a 3D spheroid morphology
• Can be used with or without scaffolds to generate 3D cell models
• Low shear force in the rotating vessel (low turbulence) allows spheroid growth
• High mass transfer of nutrients in media prevents cell death within spheroid core
• Ability to vary rotation speed with tachometer

3D Cell culture applications using the RCCS:

• Stem cell maintenance
• Stem cell expansion
• Stem cell differentiation
• Host-pathogen studies
• Cancer modeling/ tumor spheroid culture
• Cancer cell invasion studies
• Tissue engineering
• Spheroid formation and culture
• Recellularization
• Decellularization
• Explant culture
• Organoid culture
• Hollow organ culture
• Blood vessel culture