NGS molecular diagnostics

454 MID kits - Multiplicom

These kits are to be used for the second PCR step to incorporate barcoding and adaptors required for 454 GS Junior or 454 GS FLX instruments (Roche).

ADH MASTR v2 - Multiplicom

The ADH MASTR v2 is a molecular assay (research use only) for the identification of all SNVs and CNVs in LDLR, PCSK9, APOE, part of exon 26 (c.10200 to c.11100) of APOB and 12 SNPs underlying Autosomal Dominant Hypercholesterolemia.

ALPORT MASTR - Multiplicom

The ALPORT MASTR amplifies the coding regions of the genes COL4A3, COL4A4 and COL4A5.

BRCA Hereditary Cancer MASTR Plus - Multiplicom

The BRCA Hereditary Cancer MASTR Plus is a molecular assay for the identification of all mutations and CNVs in the 26 selected genes.

BRCA HP - Multiplicom

A homopolymer assay for MASTR™ assays to allow rapid detection of small insertion/deletion mutations in the coding homopolymer stretches of the targeted genes.

BRCA MAQ - Multiplicom

The BRCA MAQ assay is intended for CNV detection in the BRCA1 and BRCA2 genes.

BRCA MASTR Dx - Multiplicom

BRCA MASTR™ Dx is a CE-IVD labeled molecular diagnostic assay for the identification of mutations in the coding regions of BRCA1 and BRCA2 in individuals with increased risk for breast, ovarian and/or related cancers.

BRCA Tumor MASTR™ Plus Dx - Multiplicom

BRCA Tumor MASTR™ Plus Dx is a CE-IVD-labeled molecular diagnostic assay for the identification of mutations in the coding regions of the BRCA1 and BRCA2 genes in cancer patients.

BRCA Tumor MASTR Plus - Multiplicom

BRCA Tumor MASTR™ Plus (RUO) is a molecular assay for the identification of mutations in the coding regions of the BRCA1 and BRCA2 genes in cancer patients.

CFTR HP - Multiplicom

A homopolymer assay for MASTR™ assays to allow rapid detection of small insertion/deletion mutations in the coding homopolymer stretches of the targeted genes.

CFTR MASTR Dx - Multiplicom

The CFTR MASTR™ Dx is a molecular diagnostic assay for identification of sequence variants covering the complete CFTR gene in individuals with increased risk for CF, in CF-carriers or CF-related phenotypes.

Clarigo - Multiplicom

Clarigo™ is a CE marked non-invasive prenatal test (NIPT), specifically designed for implementation in local clinical laboratories to enable NIPT for all.

CLL MASTR Plus - Multiplicom

The CLL MASTR Plus is a molecular assay for the identification of both SNVs and CNAs in 9 selected genes in individuals with indication of Chronic lymphocytic leukemia (CLL).

DMD MASTR - Multiplicom

The DMD MASTR assay amplifies the coding region of the DMD gene implicated in Duchenne Muscular Dystrophy (DMD).

drMID for Illumina NGS systems - Multiplicom

The drMID for Illumina NGS systems is developed for incorporating molecular identifiers (MIDs) and adaptors into amplicons of MASTR-based assays, enabling Next-Generating Sequencing (NGS) in 2 directions (dual read) on all Illumina NGS platforms.

EGFR 18-21 MASTR - Multiplicom

The EGFR MASTR assay amplifies exons 18 to 21 of the EGFR gene and consists of 4 amplicons in a single multiplex PCR reaction.

FAP HP - Multiplicom

A homopolymer assay for MASTR™ assays to allow rapid detection of small insertion/deletion mutations in the coding homopolymer stretches of the targeted genes.

FAP MASTR - Multiplicom

FAP MASTR™ is a molecular assay for the identification or confirmation of the presence or absence of mutations in the complete coding regions of the APC and MUTYH genes.

FMF MASTR Dx - Multiplicom

The FMF MASTR Dx is a molecular diagnostic assay for the identification of all mutations in the Mediterranean Fever (MEFV) gene underlying FMF.

GIST MASTR - Multiplicom

The GIST MASTR assay amplifies exons 9, 11, 13, 14, 15, 16, 17 of the KIT gene and exons 8, 10, 12, 14, 18 of the PDGFRA gene.

HCM MASTR - Multiplicom

The HCM MASTR assay amplifies the entire coding regions of MYBPC3, MYH7, TNNI3, TNNT2, and MYL2 genes.

HNPCC HP - Multiplicom

A homopolymer assay for MASTR™ assays to allow rapid detection of small insertion/deletion mutations in the coding homopolymer stretches of the targeted genes.

HNPCC MASTR Plus - Multiplicom

The HNPCC MASTR Plus is a molecular assay (research use only) for the identification of all mutations and CNVs in 4 genes (MLH1, MSH2, MSH6, and PMS2) and 3’ UTR of EPCAM associated with hereditary non-polyposis colorectal cancer (HNPCC).

MARFAN MASTR - Multiplicom

MARFAN MASTR is a ready to use MPS based molecular assay for early detection of FBN1 mutations. The MARFAN MASTR amplifies the coding regions of the FBN1 gene, including SNVs and CNVs, implicated in the Marfan syndrome.

MID for Illumina MiSeq® - Multiplicom

These kits are to be used in combination with the MASTR™ assays.

MID for Ion PGM™ System - Multiplicom

The kits are to be used in combination with the MASTR™ assays for the second PCR to incorporate barcoding and adaptors required for the Ion PGM™ System.

MODY MASTR - Multiplicom

The MODY MASTR assay amplifies the entire coding regions of the ABCC8, GCK, HNF1A, HNF4A, HNF1B, INS and KCNJ11 genes.

PED MASTR Plus - Multiplicom

The PED MASTR Plus is a molecular assay (research use only) for the identification of all mutations in 51 genes underlying PED.

QC Plex - Multiplicom

The QC plex assay enables the qualitative and quantitative assessment of human DNA.

Short Read Amplification kit - Multiplicom

This assay is to be used in combination with the MASTR assays, for applications on

SOMATIC 1 MASTR Plus Dx - Multiplicom

SOMATIC 1 MASTR™ Plus Dx is a CE-IVD labeled molecular diagnostic assay for the identification of mutations in NRAS, KRAS and BRAF genes in cancer patients.

SOMATIC 1 MASTR Plus - Multiplicom

The SOMATIC 1 MASTR Plus is a molecular assay (Research Use Only) for the identification of all mutations in the NRAS, KRAS and BRAF genes in individuals with various types of cancer.

SOMATIC 2 MASTR Plus - Multiplicom

The SOMATIC 2 MASTR Plus is a molecular assay for the identification of all mutations in the coding region of the EGFR, ERBB2, PIK3CA, PIK3R1 and PTEN genes in various types of solid tumors.

STARGARDT MASTR - Multiplicom

STARGARDT MASTR is a ready to use MPS based molecular assay for early detection of ABCA4, ELOVL4 and CNGB3 mutations associated with Stargardt macular dystrophy.

TP53 MASTR - Multiplicom

The TP53 MASTR identifies SNVs and small indels in the coding region of TP53.

Tumor Hotspot MASTR Plus - Multiplicom

The Tumor Hotspot MASTR™ Plus is a molecular assay (research use only) for the identification of SNVs and CNAs in frequently mutated genes in solid tumors.

WG MAQ - Multiplicom

Whole Genome (WG) MAQ is a CNV confirmation tool that enables fast and flexible CNV confirmation of individual copy number events.