Products

“The iCELLigence system provides me a fast, reliable and reproducible way to specifically monitor the suspension cell interactions with proteins of the extracellular matrix, and dynamics of its changes in response to inhibitor addition”

MSc. Adam Obr

Institute of Hematology and Blood Transfusion, Prague, Czech Republic

"We purchased the system as we had a good experience with it in past – our group works in the field of nanomedicine. In experiments, various nanomaterials (carbon, magnetic particles) are modified by antitumor drugs and other molecules for specific targeting of tumor cells.
The the greatest benefit of the system is that the experiments are easy to set up, the data are obtained in a relatively short time without the need for more complicated sample manipulation. The method makes it possible not only to monitor the increasing number of cells, but also to evaluate the progress of this process - to elegantly determine the growth characteristics of the studied cells and to test the substances used. The process is completely independent of the human factor, thereby minimizing common experimental errors."

Prof. René Kizek

University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

“We successfully employed xCELLigence system for studying migration of malignant melanoma cell lines in response to variety of agents. We were also able to employ this system to measure the invasion of HUVEC endothelial cell monolayer by melanoma cells according to this:  JOVE protocol

Dr n.farm. Artur Wnorowski

Medical University of Lublin, Department of Biopharmation

"xCELLigence system helped my research in performing real-time evaluation of the toxicological profile for several types of innovative drugs that were tested on both primary cells and standard cell lines. Additionally, this platform demonstrated high sensitivity of detection of intracellular signaling events for drugs targeting protein kinases-mediated cellular pathways."

Dr. Monica Neagu

'Victor Babeș' National Institute of Pathology, Bucharest, Romania

The xCELLigence system proved to be a unique and invaluable technology in the development of new therapeutics for the steroid hormone sensitive cancers. It enabled us to analyze detailed proliferation dynamics of various cancer cell types, in response to manipulation of complex signaling network by steroid hormone receptors and enzymes involved in the steroid hormone biosyntesis."

Dr. David Sedlák

Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

xCELLigence DP - Acea Biosciences

The technology extended into most powerful cell migration tool

The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16.It is located inside a tissue culture incubator. Each of the three 16-well plate holders can be used independently under the RTCA Software. The RTCA DP Analyzer can automatically select wells for measurement and continuously transfer measured impedance data to the computer. Cell Index values, derived from the measured impedances, are continuously displayed on the Software user interface.

The RTCA DP Instrument is composed of three main components: 

  • RTCA DP Analyzer
  • RTCA Control Unit
  • E-Plate 16 or CIM-Plates 16

RTCA DP Instrument Highlights: 

  • Highly flexible low throughput: Accommodates up to three E-Plates 16 or CIM-Plates 16 simultaneously
  • Flexibility: Independent operation of the three 16 well plates by up to three different users
  • Clear data presentation: 16-well graph shows individual Cell Index curves for all 16 wells
  • Broad range of applications for cellular assays and cell invasion migration assays

Show more

http://www.aceabio.com/product_info.aspx?id=184

Discover more

Cancer Immunotherapy Applications of xCELLigence Real-Time Cell Analysis (RTCA) Systems Use of the real time xCelligence system for purposes of medical microbiology xCELLigence cancer immunotherapy: NK cell-mediated cytolysis In vitro hypoxia studies using xCELLigence platform Real-time chemotaxis of macrophages Quantifying virus-mediated cytopathic effect with xCELLigence platform Introducing the xCELLigence Immunotherapy kit – B Cell killing assay Real-time monitoring of Human Skin-Derived Precursor (SKPs) cell differentiation Assessment of CAR T Cell killing capacity against solid tumors-Thursday, October 20, 2016, 5 pm CEST Cancer immunotherapy: Macrophage-mediated phagocytosis Monitoring in real time the formation and removal of biofilms from clinical related pathogens xCELLigence in personalized cancer medicine Investigating the hallmarks of cancer using xCELLigence system Monitoring the formation and removal of biofilms from clinically relevant pathogens in real-time Real-time determination of virus titers using cell electric impedance technology Label-free monitoring of T cell activation by the impedance-based system A novel high throughput assay for diagnosis by real-time monitoring of parasite motility Optimization of (CAR) T cell design guided by sensitive sssessment of B cell killing Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy Cellular impedance measurement- response of OVCAR-3 cells to Cisplatin and hyperthermia Automated continuous monitoring of growth factor-mediated Endothelial cell migration ACEA webinar series: Using xCELLigence RTCA to study biofilms formation Protectome analysis: A new selective tool for bacterial vaccine discovery
Riccardo Pasculli

Field Application Specialist

Riccardo

Pasculli

+420 731 127 717

Send Message

Setup a demonstration
with our specialist

Request a demo

Related products

A unique, portable, impedance-based system for cell-based assays, such as cell growth, proliferation, cytotoxicity, adhesion and morphological dynamics

show detail

The true color inverted brightfield microscopy with all of the LumaView software features of the fluorescent LumaScope

show detail

Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey