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Cellular stress induces erythrocyte assembly and promotes microangiopathy

Fluxion Biosciences

Dec 19, 2018

Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...

The need for ultra high field magnetic resonance imaging

Bruker Biospin

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MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...

Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies

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Accurate labeling of endogenous proteins for advanced light microscopy in living cells remains challenging. Nanobodies...

Squaraine fluorophore as a NIR-fluorescent probe for the in vivo detection of diagnostic enzymes

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IncuCyte neuronal activity assay

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The generation and maturation of neuronal networks are necessary characteristics of neurogenesis, providing...

The most advanced software for preclinical imaging research

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Modern imaging laboratories hosting PET/MR instruments profit from the fully integrated common imaging platform...

IZON qEV - Isolate your exosomes in just 15 minutes

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Extracellular  vesicles  (EVs)  are  prevalent  in biological  fluids  and  are  of  great  interest  to researchers ...

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COY - personalized hypoxic chambers

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When your research requires consistent atmospheric control to maintain hypoxia, normoxia, or hyperoxia, you can count...

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Better antibody discovery using IntelliCyt’s iQue Screener

May 18, 2016

With the increasing need for new therapies for cancer, autoimmune disorders and Alzheimer’s disease, monoclonal antibodies are proving very successful due to their high affinity and specificity for their target antigens. In cancer, for example, their first use was as antagonists of oncogenic receptor tyrosine kinases, but today monoclonal antibodies have emerged as vehicles for the targeted delivery of potent chemotherapeutic agents and as powerful tools to manipulate anticancer immune responses. Currently,
more than 30 antibody therapeutics are marketed worldwide. Some analysts predict that, given the rate of current revenue growth and potential new approvals, the global market could reach $58 billion by 2016. In addition, there are hundreds of monoclonal antibody-based biologic drugs in various phases of clinical trials worldwide.

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