The company provides a revolutionary cell culturing platform that replicates the physiological environment of native tissues to deliver reproducible and biologically relevant molecular analysis.
Accelerate to discover
Related topics
Cardiomyocyte isolation using Cellenion’s cellenONE instrument
Mar 24, 2023
The cellenONE platform is ideal for the isolation of fragile and heterogeneous cell size populations, such as...
Introducing Cytek Human Leukocyte Kit, the first ever 15-color lyse no-wash assay
Mar 13, 2023
This kit has been designed to enumerate all major leukocyte subsets and it mirrors and expands on those identified in a...
Immunofluorescence Imaging for Rare Cell Detection with CyteFinder II
Mar 7, 2023
CyteFinder II Instruments are high speed, whole slide imaging systems with options for liquid biopsy analysis and...
New Kit for Bacterial analysis expands capability of Guava Muse flow cytometer
Feb 20, 2023
With the Guava Muse cell analyzer, you can now achieve highly quantitative results at a fraction of the price, effort,...
Flash news - did you know, that you can use Singulator S100 also for plant research?
Feb 10, 2023
In this short TechNote you can find how Singulator can help the data quality in Single cell sequencing - now even in...
Webinar: Spatial Biology and immunofluorescence to study human pancreata in in type 1 diabete
Feb 9, 2023
In this webinar, Dr. Quesada-Masachs from La Jolla Institute for Immunology reveals the image analysis pipeline that...
Extensive assessment of Cytokine production on the NovoCyte Advanteon flow cytometer
Jan 13, 2023
Cytokines are small molecules essential for immune cell response to activation by pathogens, autoimmunity, or...
New installation of Cytek Aurora in Slovenia
Jan 11, 2023
2nd spectral flowcytometer Aurora from Cytek was installed at National Institute of Biology in Slovenia
Oct 17, 2017
The Avatar system from Xcell Biosciences was originally designed to maintain and propagate human stem cells under culturing conditions that replicate the stem cell niche. The system was modified to cultivate a variety of primary human tumor cells, including CTCs, by replicating conditions found within the tumor microenvironment. The Avatar system incorporates a unique bioreactor that regulates settings for oxygen and atmospheric pressure levels, in addition to the usual temperature and carbon dioxide controls. Complementing the novel bioreactor are serum-free, chemically defined culture media composed of recombinant human growth factors, and a CTC-capture substrate composedof a collagen-based hydrogel.
The workflow was developed in response to mounting evidence that hypoxia and pressure are influential traits in the cellular microenvironment that contribute to the maintenance and propagation of tumorcells. When complemented with an optimal cocktail of growth factors and a collagen-rich substrate found within tumor tissues, tumor cells can be maintained and propagated ex vivo, at rates similar to those observed in the body. Other studies investigatingcell morphology as well as gene and protein expression profiles have shown that cells cultured in the Avatar system more faithfully reflect in vivo biology than cells grown in traditional CO2 incubators supplemented with animal serum-based culture media.
Related technologies: Physiological cell culturing
Get more info
Brand profile
The company provides a revolutionary cell culturing platform that replicates the physiological environment of native tissues to deliver reproducible and biologically relevant molecular analysis.
More info at:
www.xcellbio.com