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Fat-water separation Imaging in Preclinical MRI

Mar 1, 2019

Non-invasive in vivo phenotyping of adipose tissue deposits in small animal models is of great importance in preclinical metabolic research. Additionally, in Magnetic Resonance Imaging (MRI), fat suppression is often performed with Radio-Frequency (RF) pulse-based fat saturation techniques to avoid artifacts arising from fat. However, RF-based fat suppression can be non-optimal especially at low magnetic fields with low chemical shifts between fat and water as well as at high fields which often have challenging shim conditions. To overcome these limitations an easy to use method to discriminate fat and water in preclinical MRI research is presented. The fully integrated method is introduced with the
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