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CASY quantifies cells and particles passing a measuring pore exposed to a low voltage electrical field. Based on a cells size and conductivity, a resistance signal is generated and recorded. Living cells generate high resistance signals due to their intact membrane structure. Dying or dead cells cause much lower resistance due to their increased membrane permeability: they are measured chart. Furthermore, cell viability is determined by automatically quantitatively comparing viable cells with dead cells, the latter being represented by the size of their nuclei in the measurement chart. In a simple, fast and dye-free measurement, the huge dynamic measuring range provides you with all aspects of the current status of your cell culture: Monitor cell debris, distinguish viable cells from dead cells, and readily observe cell clusters /aggregates – all at a single glance. With a detection range of 0.7 – 120 μm, CASY measures all types of mammalian cells and stem cells, as well as bacteria, yeast, algae, parasites, pollen, sperm and more. Any particle in the size range might be measurable – and a lot of various samples have been readily measured.
Related technologies: Cell counting
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