Accelerate to discover

Back to filter

Related topics

Introducing ExoFlex - The latest assay for customized EV detection

NanoView Biosciences

May 11, 2021

ExoFlex allows users to customize the detection of EVs via any custom antibody. Nanoview is offering the ability to...

Build your experiments online with new Spectrum Viewer and SpectroFlo Experiment Builder

Cytek Biosciences

May 5, 2021

Explore new capabilities of Cytek's Full Spectrum Viewer and complementary SpectroFlo Experiment Builder. Explore on...

IVM-MS2: the most compact IntraVital Two-Photon microscope in the world

IVIM Technology

Apr 28, 2021

IVIM Technology, Inc. has released the most compact all-in-one intravital two-photon microscope. IVM-MS2 is the world's...

Cytek Spectral cytometers : taking science one step further with 200+ Publications

Cytek Biosciences

Apr 26, 2021

Cytek Aurora is helping researchers around the world take their science further. See how in the 200+ publications in...

May 12, 2021

Anesthesia in small animals: How to optimize management?

RWD

Apr 22, 2021

Anesthesia is just a complex technique in which the administration of anesthetics drugs is the less important step.

Cytek webinar : Evaluating Spectral Cytometry for Immune Profiling in Viral Disease

Cytek Biosciences

Apr 19, 2021

In conventional fluorescence cytometry, each fluorophore in a panel is measured in a target detector, through the use...

May 12, 2021

Rethinking 3D cell culture with IncuCyte: advanced cell cultures from iPSCs and organoids

Sartorius

Apr 14, 2021

The world is neither flat nor two-dimensional, so why should cell culture be? Traditional cell culture systems grow...

Show all topics (10)

Hybrid X-Ray/Optical imaging of organic fluorophores

Sep 19, 2016

Traditional in vivo fluorescent imaging commonly employs fluorescent protein reporters, including site-directed and enzyme-activatable conjugates. Red-shifted and NIR (700 – 900 nm) fluorophore reporters are now considered mainstream for in vivo imaging applications, due to the relatively low levels of light scatter and autofluorescence when used in living specimens. Recently, there have been reports of in vivo imaging with luminescent or fluorescent probes that are X-Ray activated (Carpenter et al., 2010; Osakada et al., 2013; 2014). This hybrid X-Ray/optical approach has the potential to offer the combined deeper imaging associated with X-Ray and functional detection associated with targeted optical agents. Reports that detail hybrid X-Ray/optical imaging with organic fluorophores are exceedingly rare. Here, we provide a preliminary, in vitro evaluation of selected, commercial organic fluorophores including anthracene, carbocyanine (Cy7), Rhodamine B (Rho), Carboxyfluorescein CF), and Squaraine Rotatxane (SR) as agents for X-Ray induced fluorescence (XRIF) imaging, using the Bruker In-Vivo Xtreme imaging system.

Read more

Scientific paper
Technical breakthrough
Application

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey