Accelerate to discover

Back to filter

Related topics

Download today your IsoPlexis e-book: understanding immune Cell Function In Cancer

IsoPlexis

Dec 1, 2021

Understanding complex immune-cancer interactions is critical to identifying therapeutic targets, devising novel avenues...

IsoPlexis technology: accelerating decisions in immunotherapy with predictive single-cell response

IsoPlexis

Nov 25, 2021

The IsoLight is a hub for comprehensive functional profiling of each cell type across a large assay menu of single-cell...

Extensive assessment of Cytokine production on the NovoCyte Penteon flow cytometer

Agilent technologies

Nov 23, 2021

Cytokines are small molecules essential for immune cell response to activation by pathogens, autoimmunity, or...

Jan 26, 2022

Discover the advanced Detector Technology in Agilent NovoCyte flow cytometers

Agilent technologies

Nov 8, 2021

This technical overview describes advancements in detector technology, and highlights examples where optimal signal...

Introducing isoLight system - Automated Cellular Proteomics hub

IsoPlexis

Nov 4, 2021

The IsoLight is a hub for comprehensive functional profiling of each cell type across a large assay menu of single-cell...

Jan 26, 2022

Introducing Cytek NEW 25-Color Immunoprofiling Assay & Kit!

Cytek Biosciences

Oct 25, 2021

To unleash the power of the Cytek full spectrum cytometry system, Cytek scientists designed and developed the 25-Color...

Show all topics (10)

Hybrid X-Ray/Optical imaging of organic fluorophores

Sep 19, 2016

Traditional in vivo fluorescent imaging commonly employs fluorescent protein reporters, including site-directed and enzyme-activatable conjugates. Red-shifted and NIR (700 – 900 nm) fluorophore reporters are now considered mainstream for in vivo imaging applications, due to the relatively low levels of light scatter and autofluorescence when used in living specimens. Recently, there have been reports of in vivo imaging with luminescent or fluorescent probes that are X-Ray activated (Carpenter et al., 2010; Osakada et al., 2013; 2014). This hybrid X-Ray/optical approach has the potential to offer the combined deeper imaging associated with X-Ray and functional detection associated with targeted optical agents. Reports that detail hybrid X-Ray/optical imaging with organic fluorophores are exceedingly rare. Here, we provide a preliminary, in vitro evaluation of selected, commercial organic fluorophores including anthracene, carbocyanine (Cy7), Rhodamine B (Rho), Carboxyfluorescein CF), and Squaraine Rotatxane (SR) as agents for X-Ray induced fluorescence (XRIF) imaging, using the Bruker In-Vivo Xtreme imaging system.

Read more

Scientific paper
Technical breakthrough
Application

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey