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Responsive fluorescence probe for detection of Hypochlorous acid in live cells and animals

Spectral Instruments Imaging

Jan 17, 2019

In this work, a new fluorescence probe, PQI, was developed for monitoring of the HOCl level in biological samples. The...

Improved differentiation of Retinal Organoids stem cells derived using rotating-wall vessels

Synthecon

Jan 15, 2019

Pluripotent stem cells can be differentiated into 3D retinal organoids, with major cell types self-patterning into a...

IncuCyte webinar recording: CAR T-cell therapy, frontiers in cancer Immunotherapy

Sartorius

Jan 11, 2019

The success of immune checkpoint blockade adds new therapeutic category to Cancers are the most heterogenous group of...

CT‐analyzer plug‐ins: ROI shrink‐wrap and primitive ROI

Bruker Biospin

Jan 7, 2019

The ROI shrink‐wrap gives the possibility to automatically generate a region‐of‐interest by adapting to the shape of...

Jan 23, 2019

ACEA Biosciences launch xCELLigence RTCA software Pro for immunotherapy applications

Acea Biosciences

Dec 28, 2018

RTCA Software Pro is an integrated software package for running and analyzing real time cell analysis data from...

Cellular stress induces erythrocyte assembly and promotes microangiopathy

Fluxion Biosciences

Dec 19, 2018

Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...

The need for ultra high field magnetic resonance imaging

Bruker Biospin

Dec 17, 2018

MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...

Jan 23, 2019

Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies

Etaluma

Dec 6, 2018

Accurate labeling of endogenous proteins for advanced light microscopy in living cells remains challenging. Nanobodies...

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In vivo visualization of Candida albicans infections

Oct 30, 2017

Candida yeasts are commensals of human skin and mucosal surfaces but can also cause fungal infections. Candida albicans is a major fungal pathogen and causes life-threatening diseases especially but not limited to immuno-compromised patients. Candidiasis most often develops in the mouth or throat (called oropharyngeal candidiasis or thrush), the vagina (yeast infection) or as invasive candidiasis after entering the bloodstream and thus spreading throughout the body.
The efficacy of drugs to combat fungal infections is limited, as 40 – 60 % of infected patients still die from the disease.
There is a need for novel therapeutic approaches, and this necessitates a detailed knowledge of this fungal pathogens and of its pathogenesis (Sanglard and Odds, 2002). The In-Vivo Xtreme II proved to be a robust system to assess the progression of C. albicans disease in mice. The use of a Sealed Animal Tray is convenient and decreased risks of crosscontamination in our animal facility, especially when several types of pathogens were tested for BLI.

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Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

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