Accelerate to discover

Back to filter

Related topics

The need for ultra high field magnetic resonance imaging

Bruker Biospin

Dec 17, 2018

MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...

NovoCyte Quanteon webinar: In-depth cell Proliferation through new advances in flow cytometry

Acea Biosciences

Dec 11, 2018

Cell proliferation is one of the most fundamental biological processes in biology. Many of the traditional assays to...

Webinar: early detection of metabolic remodeling in pressure overload left ventricle Hypertrophy

Bruker Biospin

Nov 28, 2018

Do you already heard the hypothesis that metabolic changes in the heart may precede and even trigger structural and...

Squaraine fluorophore as a NIR-fluorescent probe for the in vivo detection of diagnostic enzymes

Spectral Instruments Imaging

Nov 19, 2018

An oligo(ethylene glycol)-functionalized squaraine fluorophore has been developed as an NIR-fluorescent probe that can...

Dec 19, 2018

IncuCyte neuronal activity assay

Sartorius

Nov 13, 2018

The generation and maturation of neuronal networks are necessary characteristics of neurogenesis, providing...

The most advanced software for preclinical imaging research

Bruker Biospin

Nov 7, 2018

Modern imaging laboratories hosting PET/MR instruments profit from the fully integrated common imaging platform...

IZON qEV - Isolate your exosomes in just 15 minutes

IZON

Oct 25, 2018

Extracellular  vesicles  (EVs)  are  prevalent  in biological  fluids  and  are  of  great  interest  to researchers ...

Dec 19, 2018

COY - personalized hypoxic chambers

COY laboratory products

Oct 18, 2018

When your research requires consistent atmospheric control to maintain hypoxia, normoxia, or hyperoxia, you can count...

Show all topics (10)

Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies

Dec 6, 2018

To facilitate an expanded application, researchers present a scalable and high-throughput strategy tosimultaneously target multiple endogenous proteins in living cells with micro- to nanometer resolution. Forintracellular protein labeling, they advanced nanobodies by site-specific and stoichiometric attachment ofbright organicfluorophores. Their fast andfine-tuned intracellular transfer by microfluidic cell squeezingenabled high-throughput delivery with less than 10% dead cells. This strategy allowed for the dual-colorimaging of distinct endogenous cellular structures, and culminated in super-resolution imaging of nativeprotein networks in genetically non-modified living cells. The simultaneous delivery of multipleengineered nanobodies does not only offer exciting prospects for multiplexed imaging of endogenousprotein, but also holds potential for visualizing native cellular structures with unprecedented accuracy.

Read more!

Scientific paper
Application

Related technologies: Time-lapse microscopy

Get more info

Riccardo Pasculli

Head of application support

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

Etaluma

With a focus on portability, ease of use, high-quality imaging and fast frame-rate, Etaluma developed new concept in simple, affordable, and accessible fluorescence microscopy.

Related products

The true color inverted brightfield microscopy with all of the LumaView software features of the fluorescent LumaScope

show detail

The original single color 488nm excitation fluorescence inverted microscopy

show detail

Lumascope 620 offers a larger sensor and 3-color fluorescence for the most powerful microscope offered anywhere at this price

show detail

Blue, green & red fluorescence and walk-away automation

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey