Accelerate to discover

Back to filter

Related topics

Hypoxia in the Tumor Immune Microenvironment (TIME)

Bruker Biospin

Jun 6, 2024

Thursday, 11 July 2024, 16:00 CET | 10:00 EST
Zaver M. Bhujwalla, PhD...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

Jun 5, 2024

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

Bruker Biospin

Jun 4, 2024

MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...

Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics

Spectral Instruments Imaging

Jun 3, 2024

Disha Moholkar of University of Louisville's Gupta Lab
Tuesday, June 11, 2024, 6:30 PM
...

Jun 24, 2024

Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

Cell Microsystems

May 27, 2024

Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...

High-frequency Ultrasound System For Preclinical Imaging

S-Sharp

May 13, 2024

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

“Range+T “ for Tight Sizing of HMW Libraries

Sage Science

May 10, 2024

We decided to do a deep dive into Range+T to get a better handle the method, and to develop best practices for using...

Jun 24, 2024

April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies

IVIM Technology

May 8, 2024

Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded...

Show all topics (10)

Multi-modal PET drives interdisciplinary preclinical imaging

Feb 23, 2022

Preclinical imaging (PCI) plays a vital role in understanding the biological processes behind disease states at the organ, tissue, cell and molecular level. Elucidating how the body responds to physiological or environmental change is important in the search for therapeutic agents to fight disease. PCI is also critical to the evaluation of new treatment effectiveness and safety, by informing researchers of drug distribution patterns in tissues. PET in preclinical studies enables users to conduct repeat experiments on the same animal subjects, providing strong statistically valuable data and therefore reducing the number of animals required for a study. For this reason, it has becoming increasingly important to use non-invasive in vivo imaging techniques to optimize the use of each animal used.

Multi-modal tomographs, such as PET/CT, allow the correlation of the functional imaging obtained using PET with the anatomic imaging obtained with CT scanning. PET can also be combined with other technologies, such as magnetic resonance imaging (MRI), to bring functional imaging together with soft tissue morphological imaging. PET/MR is gaining ground in preclinical imaging applications, as it offers superior soft tissue contrast, imaging without the CT’s ionizing radiation risk, and multiparametric data.

Do you want to learn more? Just ask us!

 

Scientific paper
Application

Related technologies: Magnetic resonance imaging

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 210 323 421

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

MRI and PET imaging combined for the best of both worlds

show detail

Multi-purpose high field MRI/MRS research systems, designed for the preclinical imaging and molecular MRI

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey