Accelerate to discover

Back to filter

Related topics

Introducing Amnis AI Image Analysis software

Luminex

Aug 4, 2020

Amnis AI Image Analysis Software combines the power of high dimensional data reduction with artificial intelligence,...

Micro-CT: Fancy gadget or indispensable technology towards quantification of lung diseases?

Bruker Biospin

Jul 29, 2020

Technology allowing evaluation of live animals repeatedly is indispensable to gain better insight into the dynamics of...

Become an expert of super-resolution microscopy at

ONI

Jul 27, 2020

ONI's "ONIversity" brings the most advanced fluorescence microscopy methods to a whole new community of researchers,...

IncuCyte live-cell analysis sytem progress COVID 19 vaccine research

Sartorius

Jul 20, 2020

By putting COVID19 vaccine virus together with cells that have the ACE2 receptor at Humane Genomics Inc they can see if...

Aug 5, 2020

Breakthrough discoveries from shear flow assays for Platelet biology and vascular studies

Fluxion Biosciences

Jul 17, 2020

After a short introduction on the physio-pathological roles of platelets and the importance of their cell adhesion...

Centrifugation of suspension cells is a problem!

Curiox

Jul 8, 2020

Do you think that centrifuging cells at 500 x g is not going to cause issues? Moreover, sample prep involving...

IncuCyte webinar: Advances in 3D cell models for cancer biology

Sartorius

Jul 1, 2020

Get answers to your questions on 3D spheroid-based drug discovery, organoid research and working with advanced cell...

Aug 5, 2020

Bruker MicroCT systems supporting quality control for refurbished FFP masks

Bruker Biospin

Jun 29, 2020

In the effort to tackle the coronavirus pandemic, Bruker is proud that its instruments are being used to ensure quality...

Show all topics (10)

Nanomedicine research relying on IZON products

Feb 23, 2016

InnoMedica, a Swiss nanomedicine company led by Dr. Peter Halbherr, is working towards developing a new nanocarrier platform to transport anti-cancer drugs directly to tumours, thereby avoiding the toxic effect of the drug on healthy cells. The platform will deliver existing active agents, initially Doxorubicin, encapsulated in liposomes.

The use of Doxorubicin in liposomes is well established and now off patent, being originally released as Doxil. InnoMedica’s innovative step is to attach glycans to the surface of the liposomes. Glycans are polymers of carbohydrates, also known as polysaccharides. As an imitation of the detection system of inflammation sites of the immune system, the patented glycan based targeting quickly brings the drug to the cancer site - resulting in a better efficacy, lower dosage and less side effects.

The team at InnoMedica is developing the targeting platform with a first application called Talidox (Targeted Liposomal Doxorubicin). With the release of this drug, InnoMedica aims to improve cancer treatment of many cancer patients receiving chemotherapy. Talidox is now in the preclinical phase; however, research results suggest that cancer patients should have access to Talidox soon.

The Talidox product is developed and produced in the company’s clean room in Marly, Switzerland. One of their first analytical instruments was Izon Science’s qNano. Since last year, researchers at InnoMedica use the qNano to measure the number, size and zeta potential of their liposomes. Unlike dynamic light scattering (DLS), Tunable Resistive Pulse Sensing (TRPS) allows researchers to accurately and simultaneously measure the size and the number of individual liposomes and to provide a real number based distribution. This enables product development and manufacture to be performed with confidence. Pascal Halbherr, InnoMedica’s Production Project Leader said “Getting the qNano into our lab was a turning point and allowed us to be certain about what we were actually producing”.

Application

Related technologies: Nano and micro particle analysis

Brand profile

IZON

IZON designs and manufactures precision instrumentation for nano- and micro-scaled particle analysis.

Related products

Uses unique nanopore-based detection to enable the physical properties of a wide range of particle types to be accurately measured

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey