Accelerate to discover

Back to filter

Related topics

New technologies to uncover the molecular basis of disorders of sex development

BioNano Genomics

Aug 16, 2018

Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel...

Differentation displacement in acute myeloid leukemia through enhancer activation

Acea Biosciences

Aug 7, 2018

Blast cell differentation is inhibitited by pharmacological targeting of lysine specific demethylase 1 (LSD1). In this...

Great ape genomes laid bare

BioNano Genomics

Aug 3, 2018

Scientists have long been interested in the functional genetic differences that distinguish humans from other ape...

Dynamic PET imaging and special focus in cardiac kinetic analysis

Bruker Biospin

Aug 1, 2018

Micro-computed tomography, or micro-CT, is being employed by a rapidly increasing number of laboratories for bone...

Aug 18, 2018

Novel insights on the mechanical properties of IFs using LUMICKS’ technology

LUMICKS

Jul 30, 2018

The journal Science Advances has recently published the paper ‘Viscoelastic properties of vimentin originate from...

IncuCyte S3 Cell-by-Cell analysis software

Sartorius

Jul 27, 2018

The IncuCyte S3 Live-Cell Analysis System, "Cell-by-Cell Analysis" software module, and IncuCyte reagents provide a...

xCELLigence AccuWound 96 - Is your Wound Healing assay due for an upgrade?

Acea Biosciences

Jul 26, 2018

Cell migration and invasion are critical to many biological fields. Scratch assay with AccuWound 96 brings...

Aug 18, 2018

Image filtering and Image enhancement

Bruker Biospin

Jul 24, 2018

This issue of Bruker MicroCT Academy is focused on image filtering and enhancement of the picture. Having problems with...

Show all topics (10)

Nanomedicine research relying on IZON products

Feb 23, 2016

InnoMedica, a Swiss nanomedicine company led by Dr. Peter Halbherr, is working towards developing a new nanocarrier platform to transport anti-cancer drugs directly to tumours, thereby avoiding the toxic effect of the drug on healthy cells. The platform will deliver existing active agents, initially Doxorubicin, encapsulated in liposomes.

The use of Doxorubicin in liposomes is well established and now off patent, being originally released as Doxil. InnoMedica’s innovative step is to attach glycans to the surface of the liposomes. Glycans are polymers of carbohydrates, also known as polysaccharides. As an imitation of the detection system of inflammation sites of the immune system, the patented glycan based targeting quickly brings the drug to the cancer site - resulting in a better efficacy, lower dosage and less side effects.

The team at InnoMedica is developing the targeting platform with a first application called Talidox (Targeted Liposomal Doxorubicin). With the release of this drug, InnoMedica aims to improve cancer treatment of many cancer patients receiving chemotherapy. Talidox is now in the preclinical phase; however, research results suggest that cancer patients should have access to Talidox soon.

The Talidox product is developed and produced in the company’s clean room in Marly, Switzerland. One of their first analytical instruments was Izon Science’s qNano. Since last year, researchers at InnoMedica use the qNano to measure the number, size and zeta potential of their liposomes. Unlike dynamic light scattering (DLS), Tunable Resistive Pulse Sensing (TRPS) allows researchers to accurately and simultaneously measure the size and the number of individual liposomes and to provide a real number based distribution. This enables product development and manufacture to be performed with confidence. Pascal Halbherr, InnoMedica’s Production Project Leader said “Getting the qNano into our lab was a turning point and allowed us to be certain about what we were actually producing”.

Application

Related technologies: Nano and Micro Particle Analysis

Brand profile

IZON

IZON designs and manufactures precision instrumentation for nano- and micro-scaled particle analysis.

Related products

Uses unique nanopore-based detection to enable the physical properties of a wide range of particle types to be accurately measured

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey