Accelerate to discover

Back to filter

Related topics

Assessment of myocardial dynamics using photoacoustics & cardiac elastography

VisualSonics FujiFilm

May 17, 2019

Are you interested in Principles of Photoacoustic (PA) Imaging, and its application in cardiovascular research? Don’t...

Webinar recording: Detecting cancer-associated structural variants using Bionano optical maps

BioNano Genomics

May 15, 2019

Bionano’s genome mapping technology directly observes long molecules from 150,000 bp to megabase pair lengths to...

Cell by cell lung cancer marker profiling using high-parameter spectral flow cytometry

Cytek Biosciences

May 2, 2019

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80-85% cases of lung cancer....

In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

Spectral Instruments Imaging

Apr 26, 2019

As a trace element nutrient, cobalt is critical for both prokaryotes and eukaryotes. In the current study, a turn-on...

May 23, 2019

IncuCyte webinar recording: Human Neurons in vitro, next-gen models for neurological disease

Sartorius

Apr 23, 2019

The ability to generate and manipulate human neurons in vitro is an exciting advance that enables the validation,...

Synthesis and characterization of functional nanofilm-coated live Immune cells using CQ1

Yokogawa

Apr 10, 2019

Layer-by-layer assembly techniques have been extensively studied in cell biology because of their simplicity of...

Product update: The high pass plus cassette

Sage Science

Apr 9, 2019

The high pass plus gel cassette is the newest addition to the Pippin family. It is dedicated to the BluePippin...

May 23, 2019

Comprehending diseased cardiac mechanics using speckle tracking echocardiography

VisualSonics FujiFilm

Apr 4, 2019

Are you working with high ultrasound imaging and are you interesting in speckle tracking echocardiography (STE)? Watch...

Show all topics (10)

Nanomedicine research relying on IZON products

Feb 23, 2016

InnoMedica, a Swiss nanomedicine company led by Dr. Peter Halbherr, is working towards developing a new nanocarrier platform to transport anti-cancer drugs directly to tumours, thereby avoiding the toxic effect of the drug on healthy cells. The platform will deliver existing active agents, initially Doxorubicin, encapsulated in liposomes.

The use of Doxorubicin in liposomes is well established and now off patent, being originally released as Doxil. InnoMedica’s innovative step is to attach glycans to the surface of the liposomes. Glycans are polymers of carbohydrates, also known as polysaccharides. As an imitation of the detection system of inflammation sites of the immune system, the patented glycan based targeting quickly brings the drug to the cancer site - resulting in a better efficacy, lower dosage and less side effects.

The team at InnoMedica is developing the targeting platform with a first application called Talidox (Targeted Liposomal Doxorubicin). With the release of this drug, InnoMedica aims to improve cancer treatment of many cancer patients receiving chemotherapy. Talidox is now in the preclinical phase; however, research results suggest that cancer patients should have access to Talidox soon.

The Talidox product is developed and produced in the company’s clean room in Marly, Switzerland. One of their first analytical instruments was Izon Science’s qNano. Since last year, researchers at InnoMedica use the qNano to measure the number, size and zeta potential of their liposomes. Unlike dynamic light scattering (DLS), Tunable Resistive Pulse Sensing (TRPS) allows researchers to accurately and simultaneously measure the size and the number of individual liposomes and to provide a real number based distribution. This enables product development and manufacture to be performed with confidence. Pascal Halbherr, InnoMedica’s Production Project Leader said “Getting the qNano into our lab was a turning point and allowed us to be certain about what we were actually producing”.

Application

Related technologies: Nano and micro particle analysis

Brand profile

IZON

IZON designs and manufactures precision instrumentation for nano- and micro-scaled particle analysis.

Related products

Uses unique nanopore-based detection to enable the physical properties of a wide range of particle types to be accurately measured

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey