Accelerate to discover

Back to filter

Related topics

Vizgen webinar: spatial relationships in Developmental Biology

Vizgen

Nov 21, 2023

MERFISH integrates spatial transcriptomics technology with high resolution spatial imaging, In this webinar we will...

ACCELA educational webinar: Drive key insights and discoveries with new live cell analysis applications for eSight

Agilent technologies

Nov 14, 2023

The xCELLigence RTCA eSight enables simultaneous real time biosensor impedance-based and...

NanoCellect webinar: Plant Potential - Gentle Cell Sorting for Enhanced Plant Biology Workflows

NanoCellect

Nov 3, 2023

Gentle cell sorting is a useful tool to increase the efficiency of plant biology workflows that include gene...

Single Cell Deposition: the cornerstone of Flow Cytometry for cellular analysis and manipulation

NanoCellect

Nov 2, 2023

One notable technology for harnessing the power of single cell deposition is the NanoCellect WOLF G2 Cell Sorter and N1...

Nov 28, 2023

Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

Fluxion Biosciences

Oct 31, 2023

Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...

Single Cell Deposition: the cornerstone of Flow Cytometry for cellular analysis and manipulation

NanoCellect

Oct 30, 2023

One notable technology for harnessing the power of single cell deposition is the NanoCellect WOLF G2 Cell Sorter and N1...

Validation of an orthotopic non-small cell lung cancer mouse model to use in radiotherapy studies

Precision X-Ray

Oct 30, 2023

The use of pre-clinical orthotopic mouse models is essential for the development of novel therapies targeting solid...

Nov 28, 2023

Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy

Spectral Instruments Imaging

Oct 20, 2023

To assess tumour growth, mice were imaged using the AMI-HTX bioluminescent imaging system (Spectral Instruments...

Show all topics (10)

New type of MRI reporter taps water channel protein to image genetic activity

Aug 2, 2017

Aquaporin is a natural protein that controls the flow of water molecules into and out of cells. When it is joined with a gene researchers want to study, the result is a reporter gene. If the gene is expressing - if it is active and “on” - aquaporin levels go up, increasing the movement of water molecules. Diffusion-weighted MRI is well-suited to mapping water activity and renders an image that is darker in areas of genetic activity.
The new method overcomes many of the limits and challenges of existing reporter genes and MRI techniques. For instance, unlike some metal-based procedures, water molecules are plentiful in all cells and don’t pose the potential for toxicity that metals do. Compared to other procedures, such as the chemical exchange saturation transfer (CEST) process, MR images based on water activity can be rendered using common parameters on standard MRI scanners commonly found in labs and clinics.

Read more

Scientific paper
Technical breakthrough
Application

Related technologies: Magnetic resonance imaging

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 210 323 421

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

Multi-purpose, preclinical MRI and MRS research system

show detail

Multi-purpose high field MRI/MRS research systems, designed for the preclinical imaging and molecular MRI

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey