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Cell plasticity associated to circulating tumor cells from prostate cancer patients

Fluxion Biosciences

Mar 13, 2019

Treatment resistance is associated with tumor cells molecular plasticity. In metastatic castration resistant prostate...

Izon qEV - The fastest & most effective Exosome isolation

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Extracellular  vesicles  (EVs)  are  prevalent  in biological  fluids  and  are  of  great  interest  to researchers ...

Enhanced uptake of luminescent quantum dots by live cells

Etaluma

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The steady progress made over the past threedecades in growing a variety of inorganic nanomaterials, with discreet...

Fat-water separation Imaging in Preclinical MRI

Bruker Biospin

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Non-invasive in vivo phenotyping of adipose tissue deposits in small animal models is of great importance in...

Mar 19, 2019

New technique for dynamic monitoring of liquid tumor Cytotoxicity

Acea Biosciences

Feb 12, 2019

To develop and validate immuno-oncology therapies, scientists must understand the full dynamics of cytotoxic effectors...

Small animal 13C-hyperpolarized MRI

Bruker Biospin

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13C-Hyperpolarized molecules provide a unique signature for molecular processes relevant to a range of disease...

Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts

Spectral Instruments Imaging

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Pancreatic ductal adenocarcinoma has been increasing by 0.5% per year in the United States. This study describes the...

Mar 19, 2019

Etaluma can now offer integrated tablet for LS460/560/620 scopes

Etaluma

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Based on the customer requests of tablet mount configuration for sterile picking in the hood, Etaluma can now offer the...

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Non-invasive fluorescence imaging of infiltration in a mouse model of acute lung inflammation

Nov 29, 2016

The presence of bacterial endotoxin, lipopolysaccharide (LPS) in the lung can induce a major inflammatory response leading to acute lung injury. LPS is thought to immediately activate resident macrophages, leading to the production of various cytokines, including TNF-α. This will, in turn, prompt the recruitment of inflammatory cells, mainly neutrophils, into the lung through increases in capillary permeability and alveolar edema.1 Neutrophil infiltration into the lung can be monitored by certain, activatable (smart) fluorescent probes. This study evaluates the use of an activatable optical probe that is
optically silent upon inhalation and produces a fluorescent signal only after selective cleavage by the serine protease elastase produced by neutrophils.

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